Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates

Open Access

Year : 2021 | Volume : | Issue : 2 | Page : 25-31
By

    Salimah Aboulqasim Al

  1. Najat Ramadan Elzawi

  2. Abdelhamid Mohamed Elyassiry

  1. Lecturer, Department of Zoology, Faculty of Science, University of Sabha, Sabha, Libya, North Africa
  2. Lecturer, Department of Zoology, Faculty of Science, University of Benghazi, Benghazi, Libya, North Africa
  3. Lecturer, Department of Zoology, Faculty of Education, University of Benghazi, Benghazi, Libya, North Africa

Abstract

Antibacterial resistance has brought an urgent need to find a solution to the problem of antibacterial resistance and increase the effectiveness of antibiotics. Therefore, our current study was aimed to test the three concentrations viz., 0.5 mg/ml, 5 mg/ml and 50 mg/ml of Azo-Schiff base against Grampositive bacteria—Bacillus cereus, Micrococcus lutes, Staphylococcus aureus—to compare the effects of Schiff base alone or along with antibiotics on the viability of bacteria. Our results showed no antibacterial activity of Schiff base (L2) against three bacterial strains except S. aureus at concentration of 50 mg/ml. Synergistic effects of Schiff base was observed against B. cereus with only antibiotics CN10, but antagonistic effects was observed at all concentrations with all antibiotics.

Keywords: Resistance, Schiff base, synergistic effect, antagonistic effect, antibacterial

[This article belongs to Research & Reviews: A Journal of Microbiology & Virology(rrjomv)]

How to cite this article: Salimah Aboulqasim Al, Najat Ramadan Elzawi, Abdelhamid Mohamed Elyassiry Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates rrjomv 2021; 11:25-31
How to cite this URL: Salimah Aboulqasim Al, Najat Ramadan Elzawi, Abdelhamid Mohamed Elyassiry Synergistic and Antagonistic Effects of Azo-Schiff Base with Some Antibiotics on Gram-Positive Bacterial Isolates rrjomv 2021 {cited 2021 Aug 27};11:25-31. Available from: https://journals.stmjournals.com/rrjomv/article=2021/view=92433

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Regular Issue Open Access Article
Volume 11
Issue 2
Received March 17, 2021
Accepted May 20, 2021
Published August 27, 2021