Akansha Vyas
Gulab Kanwar
Mukesh Vijayvergia
Madhu Shekhar Bissa
Varsha Nagar
- PG Resident, Government Medical College (Kota), Kota, Rajasthan, India
- Principal and Controller, Government, Medical College, Rajasthan, India
- Deputy Director, Salumber Government Hospital Udaipur, Rajasthan, India
- Senior Resident, Government Medical College, Rajasthan, India
- PG Resident, Government Medical College, Rajasthan, India
Abstract
Diabetes mellitus is a prevalent endocrine metabolic condition that causes significant morbidity and mortality globally. Innumerable metabolic processes within our bodies depend on thyroid hormones. Excess or deficiency in insulin or thyroid hormones might cause functional problems. The intricate relationship between thyroid disorders and diabetes has been recognized for a considerable period. Patients with diabetes have been known to experience thyroid malfunction, the most prevalent kind of which is hypothyroidism. Thyroid issues are more common in diabetics than in the general population. Diabetes mellitus and its consequences are more difficult to treat when thyroid function is altered. The present study was conducted from November 2022 to August 2023 at the Department of Biochemistry, NMCH and MBS Central Laboratory, Government Medical College, Kota, Rajasthan, India. The research participants comprised of 50 individuals with Type 2 Diabetes and 50 healthy controls without diabetes, aged between 40 and 70 years. Thyroid function assessment for all subjects involved testing the thyroid profile, which includes triiodothyronine, thyroxine, and thyroid-stimulating hormone. The observations and interpretations were documented, and the findings were statistically evaluated. It was shown that just 72% of diabetes patients had normal thyroid function. Hypothyroidism was more common than hyperthyroidism among individuals with thyroid disorders (26% versus 2%, respectively). Following additional evaluation for primary and subclinical thyroid disorders, it was shown that among individuals with diabetes, subclinical hypothyroidism (20%) was more prevalent than primary hypothyroidism (6%). Abnormal thyroid hormone levels in type 2 diabetics stem from changes in the hypothalamic–pituitary–thyroid axis, leading to significant metabolic disruptions. Regular testing for thyroid dysfunction in diabetics is crucial, as early identification and treatment can reduce morbidity rates and improve their overall quality of life.
Keywords: diabetes mellitus, hypothyroidism, hormone, thyroxine, metabolic disruptions, subclinical hypothyroidism, primary hypothyroidism
[This article belongs to Research & Reviews: A Journal of Medicine(rrjom)]
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Research & Reviews: A Journal of Medicine
| Volume | 14 |
| Issue | 01 |
| Received | January 24, 2024 |
| Accepted | February 2, 2024 |
| Published | April 18, 2024 |