A Comprehensive Review on COVID-19 Evolution and Development

Open Access

Year : 2021 | Volume : | Issue : 1 | Page : 22-33
By

    Sarepalli Sai Sathwik

  1. Tulasi Nikshitha

  2. Thipurani Murali Krishna

  1. 1Department of Biotechnology, y, Chaitanya Institute of Science and Technology (Chaitanya Deemed University), Warangal, Telangana, India

Abstract

The emerging pandemic causing flu-like symptoms in patients is caused by the novel Coronavirus that was previously called 2019-nCoV. The mutated gene of SARS-CoV was transformed to SARS-CoV-2 in animals and further transmitted to humans in the month of December 2019 in Wuhan city of China. Eventually, the novel coronavirus spread all around the globe as a highly contagious disease. COVID-19 (the illness caused by coronavirus) has affected 213 countries and territories around the world. There are about 18,852,205 new positive cases, 707,451 casualties, 12,032,508 recoveries till date that is, 05th August 2020. This virus resulted in Acute Respiratory Distress Syndrome (ARDS) and multi-organ dysfunction. Human transmissions are caused due to inhaling or by contact with viral droplets. The infected patient seems to show an incubation period of 2–14 days. Due to this ominous situation, several countries got shut down to contain the spread of novel coronavirus. This review article includes the etiology, epidemiology, detection and diagnosis, histopathology, pathophysiology of novel coronavirus. To control the virus, many drugs are in use. Short-term testing kits have been discovered by many countries using the Reverse transcriptase-polymerase chain reaction (RT-PCR) technique. Vaccines from numerous research laboratories are at the stage of human trails. This review article can be preferred for further investigation on coronavirus.

Keywords: Acute respiratory distress syndrome (ARDS), COVID-19, etiology, epidemiology, SARSCoV, SARS-CoV-2, novel Coronavirus, reverse transcriptase-polymerase chain reaction (RT-PCR)

[This article belongs to Research & Reviews : A Journal of Life Sciences(rrjols)]

How to cite this article: Sarepalli Sai Sathwik, Tulasi Nikshitha, Thipurani Murali Krishna A Comprehensive Review on COVID-19 Evolution and Development rrjols 2021; 11:22-33
How to cite this URL: Sarepalli Sai Sathwik, Tulasi Nikshitha, Thipurani Murali Krishna A Comprehensive Review on COVID-19 Evolution and Development rrjols 2021 {cited 2021 Apr 07};11:22-33. Available from: https://journals.stmjournals.com/rrjols/article=2021/view=92137

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Regular Issue Open Access Article
Volume 11
Issue 1
Received June 29, 2020
Accepted July 18, 2020
Published April 7, 2021