Patil Divyashree Kantilal
Amit Kumar R Dhankani
Mansi A Dhankani
S.P. Pawar
- Student, P.S.G.V.P., Mandal’s College of Pharmacy Shahada, Maharashtra, India
- Assistant Professor, P.S.G.V.P., Mandal’s College of Pharmacy Shahada, Maharastra, India
- Assistant Professor, P.S.G.V.P., Mandal’s College of Pharmacy Shahada, Maharastra, India
- Principal, P.S.G.V.P., Mandal’s College of Pharmacy Shahada, Maharastra, India
Abstract
This review article delves into the intricate realm of concurrent estimation of multiple compounds, with a specific emphasis on Levocetirizine and its related substances. It looks into how to improve analytical process specificity by using reverse phase high-performance liquid chromatography (RP-HPLC) in conjunction with UV detection. The study meticulously explores the intricacies of method development and validation, offering invaluable insights into the realms of precision and accuracy within pharmaceutical analysis. Throughout the discourse, the review sheds light on the nuanced methodologies employed, illustrating their efficacy in concurrently estimating multiple compounds. The emphasis on Levocetirizine and its related substances underscores the relevance and applicability of these findings within pharmaceutical contexts. By scrutinizing the method development and validation processes, the review not only highlights the technical nuances involved but also provides a comprehensive understanding of the underlying principles governing precision and accuracy in analytical procedures. The significance of the findings reverberates within the realm of pharmaceutical analysis, as they underscore the pivotal role of advanced RP-HPLC techniques. Through meticulous experimentation and analysis, the review elucidates the potential of these techniques to enhance specificity, thereby augmenting the reliability and robustness of pharmaceutical analyses. Furthermore, the insights gleaned from the study offer a roadmap for researchers and practitioners seeking to navigate the complexities of concurrent compound estimation. In essence, this review article serves as a cornerstone in the field of pharmaceutical analysis, offering a comprehensive exploration of RPHPLC methodologies for concurrent compound estimation. Its conclusions not only make a substantial contribution to the corpus of current knowledge, but they also highlight how important accuracy and precision are in pharmacological analyses. As such, it provides a seminal reference point for further research and development endeavors within this burgeoning field.
Keywords: RP-HPLC, Pharmaceutical analysis, Levocetirizine, UV detection, Method development.
[This article belongs to Research & Reviews: A Journal of Drug Formulation, Development and Production(rrjodfdp)]
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| Volume | 11 |
| Issue | 01 |
| Received | March 14, 2024 |
| Accepted | March 27, 2024 |
| Published | April 12, 2024 |