simran mishra
nazar rana
mayur kaushik
Manisha daruka
enakshi Yadav
Abstract
Needle-based instruments are advancing as a promising tool for both diagnosis and treatment within the medical realm. They possess versatility, being capable of drug delivery and fluid extraction, catering to both systemic and local requirements. Unlike traditional drug delivery methods, which necessitate repeated dosing in the oral cavity due to saliva presence, there’s a growing demand for delivery systems like needle-based devices that can offer sustained drug release orally. These devices hold potential not only in addressing oral cancers but also in dispensing anti-cariogenic and antiplaque agents, facilitating remote oral health monitoring, and administering painless and anxiety-free local anesthesia. Their manifold advantages, including enhanced compliance, alleviation of needle phobia, painlessness, safety, ease of application, and minimal invasiveness, position them to significantly impact the field of dentistry. This article provides an overview of various types of needle-based devices and their manufacturing techniques, intending to serve as a fundamental review spotlighting and suggesting numerous current and potential impactful applications across different dental disciplines.
Keywords: Microfabricated devices, microneedle, nano-patches, oral applications, needle-based devices, oral mucosal patch, dental applications.
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Research & Reviews: A Journal of Dentistry
| Volume | |
| Received | March 2, 2024 |
| Accepted | March 3, 2024 |
| Published | March 11, 2024 |