Microneedles and the paradigm shift in the field of dentistry: A Review Article

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Year : | Volume : 15 | [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] : | Page : –

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    simran mishra, nazar rana, mayur kaushik, Manisha daruka, enakshi Yadav

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Abstract

nNeedle-based instruments are advancing as a promising tool for both diagnosis and treatment within the medical realm. They possess versatility, being capable of drug delivery and fluid extraction, catering to both systemic and local requirements. Unlike traditional drug delivery methods, which necessitate repeated dosing in the oral cavity due to saliva presence, there’s a growing demand for delivery systems like needle-based devices that can offer sustained drug release orally. These devices hold potential not only in addressing oral cancers but also in dispensing anti-cariogenic and antiplaque agents, facilitating remote oral health monitoring, and administering painless and anxiety-free local anesthesia. Their manifold advantages, including enhanced compliance, alleviation of needle phobia, painlessness, safety, ease of application, and minimal invasiveness, position them to significantly impact the field of dentistry. This article provides an overview of various types of needle-based devices and their manufacturing techniques, intending to serve as a fundamental review spotlighting and suggesting numerous current and potential impactful applications across different dental disciplines.

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Keywords: Microfabricated devices, microneedle, nano-patches, oral applications, needle-based devices, oral mucosal patch, dental applications.

n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Dentistry(rrjod)]

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[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Research & Reviews: A Journal of Dentistry(rrjod)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

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How to cite this article: simran mishra, nazar rana, mayur kaushik, Manisha daruka, enakshi Yadav Microneedles and the paradigm shift in the field of dentistry: A Review Article rrjod ; :-

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How to cite this URL: simran mishra, nazar rana, mayur kaushik, Manisha daruka, enakshi Yadav Microneedles and the paradigm shift in the field of dentistry: A Review Article rrjod {cited };:-. Available from: https://journals.stmjournals.com/rrjod/article=/view=0

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References

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  1. Fernando GJ, Chen X, Prow TW. Potent immunity to low doses of influenza vaccine by probabilistic guided micro-targeted skin delivery in a mouse model. PLoS One. 2010;5(4):102-166.
  2. Deepa, D.; Rana, Nazar; Arun Kumar, K. V.1. Nonsyndromic bilateral multiple retained primary incisors in mandibular arch: Rare case report. Journal of Oral Research and Review 8(2):p 79-81, Jul–Dec 2016.
  3. Yang J, Liu X, Fu Y, Song Y. Recent advances of microneedles for biomedical applications: drug delivery and beyond. Acta Pharm Sin B. 2019;9(3):469–483.
  4. Kim YC, Park JH, Prausnitz MR. Microneedles for drug and vaccine delivery. Adv Drug Deliv Rev. 2012;64(14):1547–1568.
  5. Paderni C, Compilato D, Giannola LI, Campisi G. Oral local drug delivery and new perspectives in oral drug formulation. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012;114(3):25-34.
  6. Vadim VY. The AdminPen™ Microneedle Device for Painless & Convenient Drug Delivery. Drug Delivery Technology. 2010;10(4):32-36.
  7. Singh A, Yadav S. Microneedling: Advances and widening horizons. Indian Dermatol Online J. 2016;7(4):244‐254.
  8. Park SY, Lee HU, Lee YC, et al. Wound healing potential of antibacterial microneedles loaded with green tea extracts. Mater Sci Eng C Mater Biol Appl. 2014;42:757‐762.
  9. González García LE, MacGregor MN, Visalakshan RM et al. Self-sterilizing antibacterial silver-loaded microneedles. Chem Commun (Camb). 2018;55(2):171‐174.
  10. N Kaushik, N Srivastava, M Kaushik, V Gaurav. Efficacy of different techniques of gingival depigmentation: a comparative evaluation with a case report. Int J Laser Dent 2013;3(2):68-72.

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Subscription Review Article

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Research & Reviews: A Journal of Dentistry

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[if 344 not_equal=””]ISSN: 2230-8008[/if 344]

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Volume
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424]
Received March 2, 2024
Accepted March 3, 2024
Published

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