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Open Access
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Sadhvi Gupta, Charu Gandhi, Hari Narayan
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Abstract
nDental pulp, an intricately specialized mesenchymal tissue, possesses limited regenerative capabilities attributable to the unique anatomical arrangement and the post-mitotic nature of odontoblastic cells. The process of complete pulp amputation, subsequent disinfection of the pulp space, and the insertion of synthetic materials results in the substantial loss of dentin, leading to enduring consequences such as a non-vital and structurally weakened tooth.Nevertheless, a beacon of hope emerges in the form of regenerative endodontics, a burgeoning field within modern tissue engineering. This innovative approach has shown considerable promise by harnessing the potential of stem cells in conjunction with scaffolds and responsive molecules. In stark contrast to traditional methods that often result in irreversible damage, regenerative endodontics seeks to stimulate the inherent regenerative capacity of dental pulp, fostering the restoration of both form and function.Through strategic interventions that prioritize the preservation of tooth vitality, regenerative endodontics aims to revolutionize dental care by promoting the regeneration of damaged tissues. This forward-looking paradigm offers a transformative shift from mere restorative practices to regenerative strategies, envisioning a future where compromised teeth can be revitalized through the orchestrated collaboration of biological components. As research in this field advances, the prospect of regenerative endodontics becoming a mainstream therapeutic approach holds the promise of enhancing the longevity and quality of dental treatments
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Keywords: Regeneration; Histology of pulp; Vascular supply of pulp; Dental pulp stem cells; Angiogenesis; Scaffolds.
n[if 424 equals=”Regular Issue”][This article belongs to Research & Reviews: A Journal of Dentistry(rrjod)]
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References
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| Volume | |
| [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] | |
| Received | February 6, 2024 |
| Accepted | February 9, 2024 |
| Published |
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