A Review: Carissa Carendas Leaves: Phytochemical Constituents, Traditional Use, and Pharmacological Properties

Open Access

Year : 2021 | Volume : | Issue : 2 | Page : 1-3
By

    Sonia Singh

  1. Anjali Sahu

  1. Ph.D. Student, Department of Pharmacy, Rawtpura Sarkar University Raipur, Chhattisgarh, India
  2. Assistant Professor, Department of Pharmacy, Rugata Institute of Pharmaceutical Science, Durg, Chhattisgarh, India

Abstract

Carissa carendas called Karanda are used in many traditional systems Unani, Ayurveda, homeopathic systems. Traditionally various herbal drugs used in curing many diseases are used singly or in a combination of another herbal drugs. Carissa carendas is all part of plant-like fruit, root, leaves all parts is used to treat many diseases traditionally. Various herbal drugs individually or in combination have been recommended for the treatment of different diseases. The Caresia carendas commonly known as “Karanda” have been recognized in a different system of traditional medicine to cure various diseases. It contains several phytochemical constituents belonging to the terpenoids category. Various phytochemical constituents present in a plant like flavonoids, tannins, terpenoids, alkaloids, glycosides. The leaf part is used as Analgesic and antipyretic, anticonvulsant, anti- asthmatic, anti-arthritis, antihyperlipidemic, antioxidant, anti-hepatoprotective, antioxidant properties. A higher gross heat value of this species indicates its higher potential to be used as a good fuel source. The conclusion showed that the leaf part of the extract exhibited the highest antioxidant activity and total phenolic content. So in the future, many, more diseases control by the extract of leaf part of Carisa calendars plant-like wound healing activity, etc.

Keywords: Wound Healing, Plants, Bioactive, Leaf part, Activity

[This article belongs to Research & Reviews : Journal of Botany(rrjob)]

How to cite this article: Sonia Singh, Anjali Sahu A Review: Carissa Carendas Leaves: Phytochemical Constituents, Traditional Use, and Pharmacological Properties rrjob 2021; 10:1-3
How to cite this URL: Sonia Singh, Anjali Sahu A Review: Carissa Carendas Leaves: Phytochemical Constituents, Traditional Use, and Pharmacological Properties rrjob 2021 {cited 2021 Aug 24};10:1-3. Available from: https://journals.stmjournals.com/rrjob/article=2021/view=92073

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References

1. Nguyen, D.T., Orgill D.P., Murphy G.F. (2009). Chapter 4: The Pathophysiologic Basis for Wound Healing and Cutaneous Regeneration. Biomaterials For Treating Skin Loss. Woodhead Publishing (UK/Europe) & CRC Press (US), Cambridge/Boca Raton, p. 25-57. (ISBN 978-1-4200-9989-9/ISBN 978-1-84569-363-3).
2. Stadelmann, WK; Digenis, AG; Tobin, GR (1998). “”Physiology and healing dynamics of chronic cutaneous wounds””. American journal of surgery 176 (2A Suppl): 26S–38S. doi:10.1016/S0002-9610(98)00183-4. PMID 9777970.
3. Quinn, J.V. (1998). Tissue Adhesives in Wound Care. Hamilton, Ont. B.C. Decker, Inc. Electronic book.
4. Poquérusse, Jessie. “”The Neuroscience of Sharing””. Retrieved 16 August 2012.
5. Midwood, K.S.; Williams, L.V.; Schwarzbauer, J.E. (2004). “”Tissue repair and the dynamics of the extracellular matrix””. The International Journal of Biochemistry & Cell Biology 36 (6): 1031–1037. doi:10.1016/j.biocel.2003.12.003. PMID 15094118.
6. Hegde K, Thakker SP, Joshi AB, Shastry CS, Chandrashekhar KS. Anticonvulsant activity of Carissa carandas Linn. root extract in experimental mice. Trop J Pharm Res 2009;8:117-25.
7. Rastogi RC, Vohra MM, Rastogi RP, Dhar ML. Studies on Carissa carandas Linn. Part I. Isolation of the cardiac active principles. Indian J Chem 1966;4:132.
8. Singh B, Rastogi RP. The structure of carindone. Phytochemistry 1972;11(5):1797-801.
9. Pal R, Kulshreshtha DK, Rastogi RP. A new lignan from Carissa carandas. Phytochemistry 1975;14:2302-3.
10. Hegde K, Joshi AB. Hepatoprotective effect of Carissa carandas Linn root extract against CCl4 and paracetamol induced hepatic oxidative stress. Indian J Exp Biol 2009;47(8):660-7.
11. Ganapaty S, Bharath CH, Laatsch H. Des-N-Methylnoracronycine from, the roots of Carissa conjesta. Wight. Int J Green Pharm 2010;4(3):186.
12. Wangteeraprasert R, Likhitwitayawuid K. Lignans and a sesquiterpene glucoside from Carissa carandas stem. Helv Chim Acta 2009;92(6):1217-23.
13. Naim Z, Khan MA, Nizami SS. Isolation of a new isomer of ursolic acid from fruits and leaves of Carissa carandas. Pak J Sci Ind Res1988;31(11):753.
14. Siddiqui BS, Ghani U, Ali ST, Usmani SB, Begum S. Triterpenoidal constituents of the leaves of Carissa carandas. Nat Prod Res 2003;17(3):153-8.
15. Begum S, Syed SA, Siddiqui BS, Sattar SA, Choudhary MI. Carandinol: First isohopane triterpene from the leaves of Carissa carandas L. and its cytotoxicity against cancer cell lines. Phytochem Lett 2013;6(1):91-5.
16. Sharma A, Tiwari RK, Kaushik A, Tyagi LK, Shankar K, Virmani T, et al. Standardisation of Carissa carandas Linn: A drug used in Indian system of medicine as per WHO Guidelines. Cont J Pharm Sci 2007;1:9-14.
17. Devmurari V, Shivanand P, Goyani MB, Vaghani S, Jivani NP. A review: Carissa congesta: Phytochemical constituents, traditional use and pharmacological properties. Pharmacogn Rev 2009;3(6):375.
18. Pino JA, Marbot R, Vázquez C. Volatile flavor constituents of Karanda (Carissa carandas L.) fruit. J Essent Oil Res 2004;16(5):432-4.
19. S.N. Hasmah, A. Bhatt, C.L. Keng. (2013). Micropropagation of Asam Karanda (Carissa carandas Linn). Pertanika Journal of Tropical Agricultural Science. 36(1).
20. R. Saha, L. Hossain, U. Bose, A.A. Rahman. (2010). Neuropharmacological and diuretic activities of Carissa carandas linn. leaf. Pharmacologyonline. 2010(2): 320-327.
21. T. Agarwal, R. Singh, A.D. Shukla, I. Waris. (2012). In vitro study of antibacterial activity of Carissa carandas leaf extracts. Asian J. Plant Sci. Res. 2(1): 36-40.
22. M. Hati, B.K. Jena, S. Kar, A.K. Nayak. (2014). Evaluation of anti-inflammatory and anti-pyretic activity of Carissa carandas L. leaf extract in rats. J. Pharm. Chem. Biol. Sci. 1: 18-25.
23. Garg, Vipin Kumar, Sarvesh Kumar Paliwal, and Swapnil Sharma. “”A ALGESIC ADA Tipyretic Activities Of Aqueous Extract Of Leaves Of Carissa CARA DAS LI.”” Pharmacologyonline 1: 1109-1119 (2011)
24. MA, Dar, J. Kumar, and R. Sami. “”Anti-Arthritic Activity of Leaf of Carissa carandas (L) against Adjuvant-Induced Arthritis in Rat.”” Journal of Natural & Ayurvedic Medicine,2019
25. Yadav, Ajay, Ravi Kant Vishwakarma, and Alok Pal Jain. “”Assessment of antiasthmatic activity of Carissa carandas L. leaves.”” Adv Pharmaceutical Journal 4 (2019): 100-102.
26. Shinde, Manisha, Ritu Gilhotra, and Sanjay Chaudhari. “”Anticonvulsant And Sedative Activities Of Extracts Of Carissa Carandas Leaves.”” Journal of Drug Delivery and Therapeutics 8.5 (2018): 369-373.
27. Sumbul, S., and S. I. Ahmed. “”Anti-hyperlipidemic activity of Carissa carandas (Auct.) leaves extract in egg yolk induced hyperlipidemic rats.”” J Basic Appl Sci 8 (2012): 124-34.
28. Kumar, Vijay, et al. “”Comparative phytochemical and antioxidant activities of methanol and petroleum ether extract of Carissa carandas leaves, fruit and seed.”” Int J Res 8 (2017): 70-75.
29. Bhati, Pooja, Ajay Shukla, and Maya Sharma. “”Hepatoprotective activity of leaves extracts of Carissa carandas Linn.”” American Journal of Pharm Research 4.11 (2014): 5185-5192.
30. Begum, Sabira, et al. “”Carandinol: First isohopane triterpene from the leaves of Carissa carandas L. and its cytotoxicity against cancer cell lines.”” Phytochemistry Letters 6.1 (2013): 91-95.
31. Tenguria, Rajesh Kumar, Anand Firodiya, and Firoz Naem Khan. “”Biodiversity of endophytic fungi in leaves of Carissa carandas linn. from central region of Madhya Pradesh.”” Internatl J Appl Biol Pharm Technol 3.4 (2012): 376-380.


Regular Issue Open Access Article
Volume 10
Issue 2
Received June 11, 2021
Accepted July 23, 2021
Published August 24, 2021