Revealing the Hemodynamic Orchestra: Contrasting Analysis of Blood Flow Patterns in a Bifurcated Carotid Artery

Year: 2024 | Volume: 11 | Issue: 13 | Pages:229 - 247

By

Abdulrajak Buradi, 2. Sanjaytharan Tamilselvan, 3. MD Yousuf Ahmed Khan, 4. Kapilan N.

  1. Associate Professor, Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology, Karnataka, India
  2. UG Scholar, Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology, Karnataka, India
  3. UG Scholar, Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology, Karnataka, India
  4. Professor, Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology, Karnataka, India

Abstract

Understanding blood flow patterns in the carotid artery (CA) is crucial for detecting cardiovascular diseases. Computational fluid dynamics simulations compared non-Newtonian (non-Newt) and Newtonian (Newt) models under pulsatile and laminar flow. CA geometry was accurately designed using ANSYS Space Claim & Fusion360, and simulations were run in ANSYS Fluent. Discrepancies between non-Newt and Newt models were found, especially in bifurcation’s distal regions prone to plaque. Pressure ranged from 27.870 Pa to -107.643 Pa, showing mechanical force variations. Maximum velocity was 0.700 m/s, and some areas experienced stagnant flows. Wall shear stress (WSS) analysis revealed up to 5 Pa, indicating mechanical stress areas. This study underscores blood rheology’s role in CA hemodynamics. Comparison between non-Newt and Newt models highlighted significant differences in flow, pressure, and WSS patterns, especially where atherosclerotic plaques develop. These insights are crucial for cardiovascular disease understanding, guiding interventions, and advancing cardiovascular medicine, ultimately enhancing patient care.

Keywords:Carotid artery, Computational fluid dynamics, Newtonian, Non-Newtonian models, and Wall Shear Stress

[This article belongs to Journal of Polymer and Composites JOPC]

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References

  1. Mendieta, Jessica Benitez, et al. “The importance of blood rheology in patient-specific computational fluid dynamics simulation of stenotic carotid arteries.” Biomechanics and Modeling in Mechanobiology 19 (2020): 1477-1490.
  2. Hallad, Nitesh Basavaraj, et al. “Computational Analysis of Blood Flow in a Curved Bifurcated Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  3. Mahalingam, Arun, et al. “Numerical analysis of the effect of turbulence transition on the hemodynamic parameters in human coronary arteries.” Cardiovascular diagnosis and therapy 6.3 (2016): 208.
  4. Kumar, Nitesh, et al. “Effect of Newt and Non-newt flow in subject specific carotid artery.” Journal of Engineering Science and Technology 15.4 (2020): 2764-2780.
  5. Google Images: https://www.echelon.health/disease_detection/carotid-artery-atheroma/
  6. Švancara, Pavel, et al. “Computational Modelling of Blood Flow in the Bifurcation of Human Carotid Artery.” 3-Dimensional Modelling in Cardiovascular Disease. Elsevier, 2020. 155-175.
  7. Moradicheghamahi, Jafar, Jaber Sadeghiseraji, and Mehdi Jahangiri. “Numerical solution of the Pulsatile, Non-newt and turbulent blood flow in a patient specific elastic carotid artery.” International Journal of Mechanical Sciences 150 (2019): 393-403.
  8. Buradi, Abdulrajak, and Arun Mahalingam. “Numerical analysis of wall shear stress parameters of Newtonian pulsatile blood flow through coronary artery and correlation to atherosclerosis.” Advances in Mechanical Engineering: Select Proceedings of ICRIDME 2018. Springer Singapore, 2020.
  9. Google Images: https://www.bupa.co.uk/health-information/heart blood circulation/ischaemic-stroke
  10. Hammoud, A., E. Yu Sharay, and A. N. Tikhomirov. “Newt and Non-newt pulsatile flows through CA bifurcation based on CT image geometry.” AIP Conference Proceedings. Vol. 2171. No. 1. AIP Publishing LLC, 2019.
  11. Buradi, A., and A. Mahalingam. “Effect of stenosis severity on wall shear stress based hemodynamic descriptors using multiphase mixture theory.” Journal of Applied Fluid Mechanics 11.6 (2018): 1497-1509.
  12. Ahmadpour, Ali, and Arman Khoshnevis. “Numerical Simulation of Non-newt Blood Flow in A Three-Dimensional Non-Planar Bifurcation with Stenosis.” Amirkabir Journal of Mechanical Engineering 53.9 (2021): 4865-4886.
  13. Hallad, Nitesh Basavaraj, et al. “Computational Analysis of Blood Flow in a Curved Bifurcated Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  14. Kumar, Nitesh, et al. “Influence of blood pressure and rheology on oscillatory shear index and wall shear stress in the carotid artery.” Journal of the Brazilian Society of Mechanical Sciences and Engineering 44.11 (2022): 510.
  15. Buradi, Abdulrajak, Sumant Morab, and Arun Mahalingam. “Effect of stenosis severity on shear-induced diffusion of red blood cells in coronary arteries.” Journal of Mechanics in Medicine and Biology 19.05 (2019): 1950034.
  16. Rezazadeh, Marzieh, and Ramin Ostadi. “Numerical simulation of the wall shear stress distribution in a CA bifurcation.” Journal of Mechanical Science and Technology 36.10 (2022): 5035-5046.
  17. Dhungana, Abishek, et al. “Impact of Bifurcation and Bifurcation Angle on the Hemodynamics of Coronary Arteries.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  18. Pal, Subash Chand, Manish Kumar, and Ram Dayal. “A comparative study of patient-specific bifurcated CA with different viscosity models.” Application of Soft Computing Techniques in Mechanical Engineering. CRC Press, 2022. 215-230.
  19. Buradi, Abdulrajak, and Arun Mahalingam. “Impact of coronary tortuosity on the artery hemodynamics.” Biocybernetics and Biomedical Engineering 40.1 (2020): 126-147.
  20. Deshpande, Prahlad V., et al. “Numerical Simulation of Blood Flow Study in an Idealized Bifurcated Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  21. Perktold K, Resch M, Florian H. Pulsatile Non-newt blood flow in three-dimensional carotid bifurcation models: a numerical study of flow phenomena under different bifurcation angles. J Biomed Eng. 2022;13(6):507-515.
  22. Singh, D., and S. Singh. “A multi-scale computational study of pulsatile flow in the three dimensional human CA bifurcation.” Series on Biomechanics (2022).
  23. Ramdan, Salman Aslam, et al. “Blood Flow Acoustics in CA.” Journal of Advanced Research in Fluid Mechanics and Thermal Sciences 94.1 (2022): 28-44.
  24. Nagaharish, G. N., et al. “Blood Flow Analysis Through Bifurcated and Stenosed Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  25. Lee S-W, Steinman DA (2007) On the relative importance of rheology for image-based CFD models of the carotid bifurcation. J Biomech Eng 129:273.
  26. Dahal, Prabin, et al. “Influence of Blockage on Hemodynamics of Coronary Arteries: A Numerical Investigation.” Biennial International Conference on Future Learning Aspects of Mechanical Engineering. Singapore: Springer Nature Singapore, 2022.
  27. Liepsch, D., et al. “Measurement and calculations of laminar flow in a ninety degree bifurcation.” Journal of biomechanics 15.7 (1982): 473-485.
  28. Abugattas, C., et al. “Numerical study of bifurcation blood flows using three different non-Newtonian constitutive models.” Applied Mathematical Modelling 88 (2020): 529-549.
Journal of Polymer and Composites Cover

Journal of Polymer and Composites

ISSN: 2321–2810

Volume 11
Issue 13
Received 2023/10/30
Accepted 2023/11/20
Published 2024/03/26