Computational Analysis of Non-Newtonian Blood Flow through Bifurcated Coronary Artery: Insights into Hemodynamics and Wall Shear Stress

Open Access

Year : 2024 | Volume :11 | Special Issue : 13 | Page : 160-168
By

Abdulrajak Buradi

Md Yousuf Ahmed Khan

Sanjaytharan Tamilselvan

Kapilan N.

  1. Associate Professor Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology Karnataka
  2. UG Scholar Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology Karnataka India
  3. UG Scholar Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology Karnataka India
  4. Professor Department of Mechanical Engineering, Nitte Meenakshi Institute of Technology Karnataka India

Abstract

This abstract presents a study on the computational fluid dynamics (CFD) simulations of blood flow through a bifurcated coronary artery using non-Newtonian fluid model. The objective of this study is to investigate the hemodynamic characteristics in Bifurcated Coronary artery. The methodology involved the utilization of ANSYS SpaceClaim software for creating a geometric model of the bifurcated coronary artery. A mesh independent study was conducted to ensure the accuracy and reliability of the simulations. Fluent, a popular CFD software was employed for running the simulations, with appropriate boundary conditions set for the velocity inlet, outflow, and no-slip wall conditions. Additionally, a user-defined function file was implemented to define the velocity at the inlet. The simulations were performed using two different time step sizes: 1.15 seconds and 1.30 seconds representing two Cardiac Cycle Systole and diastole. This enabled the analysis of the temporal changes in the flow characteristics and their influence on WSS, pressure, and velocity profiles. The results obtained from the simulations were post-processed to extract the desired parameters. The analysis of the results revealed significant variations in the WSS, pressure, and velocity profiles along the bifurcated coronary artery. The pressure distribution within the artery ranged from a minimum of -406.23 Pa to a maximum of 426.55 Pa. The velocity profiles obtained during the simulations ranged from a minimum of 0 m/s to a maximum of 0.879 m/s. The wall shear stress (WSS) distribution along the arterial walls ranged from a minimum of 0 Pa to a maximum of 25 Pa. Based on the findings, it can be concluded that the temporal changes in the flow characteristics within the bifurcated coronary artery play a crucial role in determining the hemodynamic conditions. This study contributes to a better understanding of the fluid dynamics in bifurcated coronary arteries and can potentially aid in the diagnosis and treatment of cardiovascular diseases.

Keywords: Hemodynamics, Computational fluid dynamics (CFD), Wall Shear Stress (WSS), Bifurcated coronary artery, Cardiovascular diseases (CVD).

[This article belongs to Special Issue under section in Journal of Polymer and Composites(jopc)]

How to cite this article: Abdulrajak Buradi, Md Yousuf Ahmed Khan, Sanjaytharan Tamilselvan, Kapilan N.. Computational Analysis of Non-Newtonian Blood Flow through Bifurcated Coronary Artery: Insights into Hemodynamics and Wall Shear Stress. Journal of Polymer and Composites. 2024; 11(13):160-168.
How to cite this URL: Abdulrajak Buradi, Md Yousuf Ahmed Khan, Sanjaytharan Tamilselvan, Kapilan N.. Computational Analysis of Non-Newtonian Blood Flow through Bifurcated Coronary Artery: Insights into Hemodynamics and Wall Shear Stress. Journal of Polymer and Composites. 2024; 11(13):160-168. Available from: https://journals.stmjournals.com/jopc/article=2024/view=143132

Full Text PDF Download

Browse Figures

References

  1. Apostolidis, Alex J., Adam P. Moyer, and Antony N. Beris. “Non-Newtonian effects in simulations of coronary arterial blood flow.” Journal of Non-Newtonian Fluid Mechanics 233 (2016): 155-165
  2. Hallad, Nitesh Basavaraj, et al. “Computational Analysis of Blood Flow in a Curved Bifurcated Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  3. Jhunjhunwala, Pooja, Pramod Padole, and S. Thombre. “CFD analysis of pulsatile flow and non-Newtonian behavior of blood in arteries.” MCB: Molecular & Cellular Biomechanics 12.1 (2015): 37-47
  4. Mahalingam, Arun, et al. “Numerical analysis of the effect of turbulence transition on the hemodynamic parameters in human coronary arteries.” Cardiovascular diagnosis and therapy 6.3 (2016): 208.
  5. Theodorakakos, A., et al. “Simulation of cardiac motion on non-Newtonian, pulsating flow development in the human left anterior descending coronary artery.” Physics in medicine & biology 53.18 (2008): 4875
  6. Buradi, Abdulrajak, and Arun Mahalingam. “Numerical analysis of wall shear stress parameters of Newtonian pulsatile blood flow through coronary artery and correlation to atherosclerosis.” Advances in Mechanical Engineering: Select Proceedings of ICRIDME 2018. Springer Singapore, 2020.
  7. Arzani, Amirhossein. “Accounting for residence-time in blood rheology models: do we really need non-Newtonian blood flow modelling in large arteries?.” Journal of The Royal Society Interface 15.146 (2018): 20180486
  8. Buradi, A., and A. Mahalingam. “Effect of stenosis severity on wall shear stress based hemodynamic descriptors using multiphase mixture theory.” Journal of Applied Fluid Mechanics 11.6 (2018): 1497-1509.
  9. Abugattas, C., et al. “Numerical study of bifurcation blood flows using three different non-Newtonian constitutive models.” Applied Mathematical Modelling 88 (2020): 529-549.
  10. Hallad, Nitesh Basavaraj, et al. “Computational Analysis of Blood Flow in a Curved Bifurcated Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  11. Soulis, Johannes V., et al. “Non-Newtonian models for molecular viscosity and wall shear stress in a 3D reconstructed human left coronary artery.” Medical engineering & physics 30.1 (2008): 9-19
  12. Buradi, Abdulrajak, Sumant Morab, and Arun Mahalingam. “Effect of stenosis severity on shear-induced diffusion of red blood cells in coronary arteries.” Journal of Mechanics in Medicine and Biology 19.05 (2019): 1950034.
  13. Rezazadeh, M., & Ostadi, R. (2022). Numerical simulation of the wall shear stress distribution in a carotid artery bifurcation. Journal of Mechanical Science and Technology, 36(10), 5035-5046.
  14. Dhungana, Abishek, et al. “Impact of Bifurcation and Bifurcation Angle on the Hemodynamics of Coronary Arteries.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  15. Pal, S. C., Kumar, M., & Dayal, R. (2022). A comparative study of patient-specific bifurcated carotid artery with different viscosity models. In Application of Soft Computing Techniques in Mechanical Engineering (pp. 215-230). CRC Press.
  16. Buradi, Abdulrajak, and Arun Mahalingam. “Impact of coronary tortuosity on the artery hemodynamics.” Biocybernetics and Biomedical Engineering 40.1 (2020): 126-147.
  17. Perktold, K., Peter, R. O., Resch, M., & Langs, G. (1991). Pulsatile non-Newtonian blood flow in three-dimensional carotid bifurcation models: a numerical study of flow phenomena under different bifurcation angles. Journal of biomedical engineering, 13(6), 507-515.
  18. Xu, X. Y., and M. W. Collins. “Studies of blood flow in arterial bifurcations using computational fluid dynamics.” Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine 208.3 (1994): 163-175.
  19. Deshpande, Prahlad V., et al. “Numerical Simulation of Blood Flow Study in an Idealized Bifurcated Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  20. Nagaharish, G. N., et al. “Blood Flow Analysis Through Bifurcated and Stenosed Coronary Artery.” Conference on Fluid Mechanics and Fluid Power. Singapore: Springer Nature Singapore, 2021.
  21. Liu, B., and D. Tang. “Non-Newtonian effects on the wall shear stress of the blood flow in stenotic right coronary arteries.” International conference on computational & experimental engineering and sciences. Vol. 17. No. 2. 2011.
  22. Dahal, Prabin, et al. “Influence of Blockage on Hemodynamics of Coronary Arteries: A Numerical Investigation.” Biennial International Conference on Future Learning Aspects of Mechanical Engineering. Singapore: Springer Nature Singapore, 2022.
Special Issue Open Access Original Research
Volume 11
Special Issue 13
Received November 27, 2023
Accepted December 20, 2023
Published February 19, 2024
Views: 35