Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids

Open Access

Year : 2023 | Volume :10 | : 2 | Page : 51-57
By

    Priyanka T. Kare

  1. Sarika S. Malode

  2. Kalyani S. Kakad

  3. Khanderao R. Jadhav

  1. Assistant Professor, Department of Pharmacognosy, NGSPM’s College of Pharmacy, Anjaneri, Nashik, Maharashtra, India
  2. Assistant Professor, Department of Pharmaceutics, NGSPM’s College of Pharmacy, Anjaneri, Nashik, Maharashtra, India
  3. Assistant Professor, Department of Pharmacognosy, PES Modern College of Pharmacy Nigdi Pune, Maharashtra, India
  4. Assistant Professor, Department of Pharmaceutics, KCT’s R.G. Sapkal College of Pharmacy, Anjaneri, Nashik, Maharashtra State, India

Abstract

The major goal of this study is to extract, isolate, and characterize curcumin-I, a component of curcuminoids. Turmeric, or Curcuma longa Linn., plays a significant role in Ayurvedic medicine. Turmeric, or Curcuma longa Linn, is the popular name for this plant. An array of chemicals with biological activity may be more easily extracted with the help of this seasoning. Some of the compounds at play include curcuminoids and turmerone, although this is by no means a full list. When curcumin I, II, and III are combined, a process takes place that creates curcuminoids. Curcumin is a powerful anti-inflammatory, anti-HIV, anti-tumor, anti-viral, anti-cancer, anti-fungal, and anti-parasitic chemical. Some more uses are: It has also been hypothesised that this molecule has anti-parasitic and anti-fungal effects. The fact that it could potentially prevent tumour, viral, and parasite development is just frosting on the cake in terms of its therapeutic potential. In order to collect the data necessary for this study, an extraction of ground turmeric using the Soxhlet technique was performed. Separating curcumin-I from the other synthetic curcuminoids was crucial to achieving this aim. Scientists were able to effectively isolate and purify the molecule using crystallisation and chromatography. The best strategy was crystallisation.

Keywords: Curcuma longa, Curcuminoids, TLC, U.V., Mass, NMR

This article belongs to Conference Thematic special issue on advanced perspectives in Chemical sciences-2022

How to cite this article: Priyanka T. Kare, Sarika S. Malode, Kalyani S. Kakad, Khanderao R. Jadhav , Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids jopc 2023; 10:51-57
How to cite this URL: Priyanka T. Kare, Sarika S. Malode, Kalyani S. Kakad, Khanderao R. Jadhav , Extraction, Isolation, Characterization of Curcumin-I From Curcuminoids jopc 2023 {cited 2023 Jan 16};10:51-57. Available from: https://journals.stmjournals.com/jopc/article=2023/view=91602

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Conference Open Access Article
Volume 10
2
Received August 17, 2023
Accepted September 16, 2022
Published January 16, 2023