Alzheimer disorders diagnosis system design using machine learning for EEG signal

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The diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificiThe diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificity, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.ty, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.

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The diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificiThe diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificity, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.ty, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.

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The diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificiThe diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificity, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.ty, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.

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    Usha B. Patel, Vandana V. Patel

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  1. Research Scholar, Assistant Professor,Lalbhai Dalpatbhai College of Engineering, Lalbhai Dalpatbhai College of Engineering,Gujarat, Gujarat,India, India
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Abstract

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The diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificiThe diagnosis of Alzheimer’s disorders (AD), a prevalent neurological disorder, can created by utilising a range of therapeutic methods, including the electroencephalogram (EEG), which has been especially successful in the past. The objective for this study is to develop a computer-aided diagnosis tool which may recognize AD from EEG data. The EEG information was cleaned up with a band-pass elliptic digital filter to remove any interference or disruptions. The filtered signal was then divided into its frequency ranges using the Discrete Wavelet Transform (DWT) method, enabling the extraction of EEG signal characteristics. To enhance the diagnostic performance, various signal features were integrated into the DWT technique, including logarithmic band power (LBP), standard deviation, and root mean square (RMS). These features were incorporated to generate feature vectors that were utilized in the diagnosis process. In order to categorize the EEG features into their respective classes, various machine learning (ML) approaches were explored, including quadratic discriminant analysis (QDA), support vector machine (SVM), and k-nearest neighbour (KNN). The performance of these approaches was then evaluated by comparing and computing their sensitivity, specificity, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.ty, and overall diagnosis accuracy. When comparing the accuracy values, it can be observed that QDA has a higher accuracy of 97.5% compared to KNN’s accuracy of 95%.

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Keywords: Alzheimer’s Disease, Electroencephalogram, Discrete Wavelet Transform, Logarithmic Band Power, Machine Learning.

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  1. Hill JM, Lukiw WJ. Microbial-generated amyloids and Alzheimer’s disease (AD). Front Aging Neurosci [Internet]. 2015 Feb 10 [cited 2023 Apr 3];7. Available from: http://journal.frontiersin.org/Article/10.3389/fnagi.2015.00009/abstract
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  6. Koenig T, Smailovic U, Jelic V. Past, present and future EEG in the clinical workup of dementias. Psychiatry Res Neuroimaging. 2020 Dec;306:111182.
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  8. Huggins CJ, Escudero J, Parra MA, Scally B, Anghinah R, Vitória Lacerda De Araújo A, et al. Deep learning of resting-state electroencephalogram signals for three-class classification of Alzheimer’s disease, mild cognitive impairment and healthy ageing. J Neural Eng. 2021 Aug 1;18(4):046087.
  9. Pirrone D, Weitschek E, Di Paolo P, De Salvo S, De Cola MC. EEG Signal Processing and Supervised Machine Learning to Early Diagnose Alzheimer’s Disease. Appl Sci. 2022 May 26;12(11):5413.
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  11. Ramzan F, Khan MUG, Rehmat A, Iqbal S, Saba T, Rehman A, et al. A Deep Learning Approach for Automated Diagnosis and Multi-Class Classification of Alzheimer’s Disease Stages Using Resting-State fMRI and Residual Neural Networks. J Med Syst. 2020 Feb;44(2):37.
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  14. AlSharabi K, Bin Salamah Y, Abdurraqeeb AM, Aljalal M, Alturki FA. EEG Signal Processing for Alzheimer’s Disorders Using Discrete Wavelet Transform and Machine Learning Approaches. IEEE Access. 2022;10:89781–97.
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Regular Issue Subscription Original Research

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Volume 14
Issue 01
Received April 26, 2023
Accepted May 9, 2023
Published May 15, 2023

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