Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management

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Year : May 21, 2024 at 3:38 pm | [if 1553 equals=””] Volume : [else] Volume :[/if 1553] | [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] : | Page : –

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Dr. Rutuja Kumbhar

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  1. Clinical Pharmacologist Asian Heart Institute and Medical Research Centre, Kurla, Mumbai Maharashtra India
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Abstract

nInsulin’s pivotal function lies in meticulously regulating blood sugar levels, thus guaranteeing cells access to the necessary energy for optimal functionality. When there is a rise in blood sugar, after a meal, the releases insulin gets released from the pancreas to facilitate the uptake of glucose by cells. Insulin primarily acts on muscle, fat, and liver cells, promoting the uptake of glucose from the blood. Another way to store glucose for later use is as glycogen, which produces energy. Additionally, insulin also a vital role in suppressing the breakdown of stored glycogen and promoting the synthesis of proteins and fats.Glucagon, another hormone produced by the pancreas, works in opposition to insulin. Between the meals or when fasting the blood sugar levels are low. Hence the glucagon signals the lover to release stored glucose, to help maintain the normal blood glucose level. In diabetes mellitus, the body’s ability to produce or respond to insulin is impaired, leading to chronically elevated blood sugar levels. This may be harmful to the blood vessels, nerves, and organs, among other things. Insulin therapy is a mainstay of diabetes management, mainly in type 1 diabetes. It may also be used in type 2 diabetes when other treatments are not sufficient to control blood sugar levels.Based on their start, peak, and duration of action, many insulins are available for therapeutic use. These consist of insulins that act quickly, briefly, moderately, and slowly.. Some newer formulations, such as insulin analogs, offer more predictable blood sugar control and fewer side effects compared to traditional insulin.In recent years, advancements in insulin delivery systems, such as insulin pumps and continuous glucose monitors, have also improved the management of diabetes by providing more precise dosing and real-time monitoring of blood sugar levels.

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Keywords: Type 1 DM, Type 2 DM, Insulin, Blood glucose or sugar, Pancreas, Beta cells

n[if 424 equals=”Regular Issue”][This article belongs to International Journal of Virus Studies(ijvs)]

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[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in International Journal of Virus Studies(ijvs)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

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How to cite this article: Dr. Rutuja Kumbhar. Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management. International Journal of Virus Studies. May 21, 2024; ():-.

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How to cite this URL: Dr. Rutuja Kumbhar. Insulin : Comprehensive review on its Crucial Role in Metabolism and Disease Management. International Journal of Virus Studies. May 21, 2024; ():-. Available from: https://journals.stmjournals.com/ijvs/article=May 21, 2024/view=0

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References

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  1. Mandal, A. (2010, February 18). What is insulin?News-Medical. https://www.news-medical.net/health/What-is-Insulin.aspx
  2. Rahman, M. S., Hossain, K. S., Das, S., Kundu, S., Adegoke, E. O., Rahman, M. A., Hannan, M. A., Uddin, M. J., & Pang, M.-G. (2021). Role of insulin in health and disease: An update. International Journal of Molecular Sciences, 22(12), 6403. https://doi.org/10.3390/ijms22126403
  3. DiGiacinto, J., & Higuera, V. (2018, July 3). About insulin: What it is, how it works, and more. Healthline. https://www.healthline.com/health/type-2-diabetes/insulin
  4. Insulin resistance. (2017, March 9). Familydoctor.org. https://familydoctor.org/condition/insulin-resistance/
  5. Diabetes treatment: Using insulin to manage blood sugar. (2023, August 4). Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/diabetes/in-depth/diabetes-treatment/art-20044084
  6. Diabetes. (n.d.). Who.int. Retrieved April 15, 2024, from https://www.who.int/health-topics/diabetes
  7. (2023, April 18). 4 ways to take insulin. Centers for Disease Control and Prevention. https://www.cdc.gov/diabetes/basics/type-1-4-ways-to-take-insulin.html
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  11. Insulin, medicines, & other diabetes treatments. (2024, April 10). National Institute of Diabetes and Digestive and Kidney Diseases; NIDDK – National Institute of Diabetes and Digestive and Kidney Diseases. https://www.niddk.nih.gov/health-information/diabetes/overview/insulin-medicines-treatments

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[if 424 not_equal=””][else]Ahead of Print[/if 424] Subscription Review Article

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International Journal of Virus Studies

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Volume
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424]
Received April 16, 2024
Accepted May 15, 2024
Published May 21, 2024

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