Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19

Year : 2024 | Volume :01 | Issue : 02 | Page : 19-28
By

Lavanya T. Nair

Shweta Singh

Abstract

The COVID-19 pandemic has brought attention to the need for rapid, accurate, and scalable diagnostic techniques. Metagenomics, a powerful technique that enables the comprehensive analysis of genetic material from complex microbial communities, has emerged as a promising diagnostic approach for COVID-19. This article elucidates the principles of metagenomic sequencing, highlighting its ability to detect viral RNA directly from clinical samples without prior knowledge of the pathogen. Furthermore, we discuss the advantages of metagenomics over traditional diagnostic methods, including its ability to identify emerging viral variants and co-infections. Additionally, we explore the challenges and limitations associated with metagenomic diagnostics, such as bioinformatics complexity and cost considerations. Moreover, we review recent advancements in metagenomic technologies and their applications in COVID-19 surveillance, outbreak monitoring, and vaccine development. Finally, we discuss future perspectives and the potential integration of metagenomics into routine clinical practice, emphasizing its role in shaping the future of infectious disease diagnosis and management.

Keywords: Metagenomics, COVID-19 diagnostics, viral variants, bioinformatics, surveillance

[This article belongs to International Journal of Tropical Medicines(ijtm)]

How to cite this article: Lavanya T. Nair, Shweta Singh. Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19. International Journal of Tropical Medicines. 2024; 01(02):19-28.
How to cite this URL: Lavanya T. Nair, Shweta Singh. Unraveling Metagenomics: A Comprehensive Diagnostic Approach for COVID-19. International Journal of Tropical Medicines. 2024; 01(02):19-28. Available from: https://journals.stmjournals.com/ijtm/article=2024/view=145266


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Regular Issue Subscription Review Article
Volume 01
Issue 02
Received April 4, 2024
Accepted April 16, 2024
Published May 7, 2024
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