Precision in Progress: The Crucial Nexus of Instrumentation and Measurement in Biotechnology Advancements

Year : 2023 | Volume : 01 | Issue : 02 | Page : 11 19
    By

    Ushaa Eswaran,

  • Vishal Eswaran,

  1. Principal and Professor, Department of ECE, Indira Institute of Technology and Sciences, Markapur, AP, India
  2. Senior Data Engineer, CVS Health Centre, Dallas, Texas, United States

Abstract

This comprehensive review examines the critical importance of instrumentation and measurement technologies in enabling advances across diverse domains of modern biotechnology. Detailed examples are provided demonstrating how analytical tools empower quantitative biology, drive discoveries, catalyze innovations, and provide solutions to global challenges. The historical evolution of bioanalytical techniques is traced, highlighting milestones that unleashed new capabilities. Current trends and future outlook are explored, underscoring the ongoing pivotal need for precision measurement capabilities to continue pushing frontiers of biotechnology forward

Keywords: Biotechnology, Instrumentation, Measurement Technologies, Analytical Techniques, Genomics, Single-Cell Analysis, Biosensors, Microfluidics, Synthetic Biology, Molecular Engineering, Point-Of-Care Diagnostics, Wearable Sensors, AI Integration, Automation, Emerging Trends.

[This article belongs to International Journal of Molecular Biotechnological Research ]

How to cite this article:
Ushaa Eswaran, Vishal Eswaran. Precision in Progress: The Crucial Nexus of Instrumentation and Measurement in Biotechnology Advancements. International Journal of Molecular Biotechnological Research. 2023; 01(02):11-19.
How to cite this URL:
Ushaa Eswaran, Vishal Eswaran. Precision in Progress: The Crucial Nexus of Instrumentation and Measurement in Biotechnology Advancements. International Journal of Molecular Biotechnological Research. 2023; 01(02):11-19. Available from: https://journals.stmjournals.com/ijmbr/article=2023/view=128992


References

1. Lauffenburger, D. A., & Linderman, J. J. (1993). Receptors: models for binding, trafficking, and signaling. Oxford University Press.
2. Gillet, L. C., Navarro, P., Tate, S., Röst, H., Selevsek, N., Reiter, L., … & Aebersold, R. (2012). Targeted data extraction of the MS/MS spectra generated by data-independent acquisition: a new concept for consistent and accurate proteome analysis. Molecular & Cellular Proteomics, 11(6), O111–016717.
3. Rajan, S., Zou, C., Leonardo, V., Daza, E. A., Buchovecky, C., Szpankowski, L., … & Heath, J. R. (2020). Multiplexed nanowire circuits for precision amplification of biomolecular signals. Nature Nanotechnology, 15(5), 451–458.
4. Arugula, M. A., & Simonian, A. L. (2016). Recent advances in aptasensors for biomedical applications. ACS Applied Bio Materials, 2(4), 1613–1631.
5. Bolbat, A., & Liedert, C. (2020). Microfluidic-based microsystems for high-throughput bioprocess development. Engineering in Life Sciences, 20(5), 189–201.
6. D’Orazio, P. (2013). Biosensors in clinical chemistry–2011 update. Clinica Chimica Acta, 412(15-16), 1749–1761.
7. Horváth, C., & Preiss, B. (1995). High-performance liquid chromatography: A practical guide. Springer Science & Business Media.
8. Saiki, R. K., Gelfand, D. H., Stoffel, S., Scharf, S. J., Higuchi, R., Horn, G. T., … & Arnheim, N. (1988). Primer-directed enzymatic amplification of DNA with a thermostable DNA polymerase. Science, 239(4839), 487–491.
9. Shendure, J., & Ji, H. (2008). Next-generation DNA sequencing. Nature biotechnology, 26(10), 1135-1145.
10. Hossain, M. A., Brennan, C. S., & Islam, N. (2014). Glucose biosensors: The journey so far and the path ahead. Sensors, 14(12), 21129–21154.
11. Tang, X., He, Y., Tian, X., Wang, S., & Reed, S. (2015). Highly sensitive electrochemical detection of toxins: Impacts and challenges of nanomaterials. Nano Today, 10(6), 763-777.
12. Ruan, C., Shi, H., & Yu, H. Z. (2019). Biosensing: Bridging the gap between the laboratory and the field. Accounts of Chemical Research, 52(11), 3168–3177.
13. Jiang, Y., Li, Y., & Liu, X. (2019). Nanomaterial-based biosensors for microbial detection. Microchimica Acta, 186(11), 730.
14. Wang, Y., Navin, N. E., & Advances, A. (2019). Advances and applications of single-cell sequencing technologies. Molecular Cell, 58(4), 598-609.
15. Khalil, A. S., Lu, T. K., & Collins, J. J. (2010). Synthetic biology: Applications come of age. Nature Reviews Genetics, 11(5), 367–379.
16. Varshney, R. K., Singh, V. K., & Börner, A. (2019). Genomics-assisted breeding for crop improvement. Trends in Plant Science, 24(11), 1151-1165.
17. Alberts, B., Johnson, A., Lewis, J., Raff, M., Roberts, K., & Walter, P. (2017). Molecular Biology of the Cell (6th ed.). Garland Science.
18. Mullis, K. B., Faloona, F. A., Scharf, S. J., Saiki, R. K., Horn, G. T., & Erlich, H. A. (1986). Specific enzymatic amplification of DNA in vitro: The polymerase chain reaction. Cold Spring Harbor Symposia on Quantitative Biology, 51, 263–273.
19. Venter, J. C., Adams, M. D., Myers, E. W., Li, P. W., Mural, R. J., Sutton, G. G., … & Holt, R. A. (2001). The sequence of the human genome. Science, 291(5507), 1304-1351.
20. Bendall, S. C., Davis, K. L., Amir, E. D., Tadmor, M. D., Simonds, E. F., Chen, T. J., … & Nolan, G. P. (2011). Single-cell trajectory detection uncovers progression and regulatory coordination in human B cell development. Cell, 157(3), 714–725.

Regular Issue Subscription Review Article
Volume 01
Issue 02
Received 24/08/2023
Accepted 16/09/2023
Published 28/11/2023
Publication Time 96 Days
340

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