Comprehensive Overview of Carbohydrate Polymers

Year : 2024 | Volume :01 | Issue : 01 | Page : –
By

Mr.Harshal K Patil

  1. Student,Department of Pharmaceutics P S G V P M `s College of Pharmacy, Shahada, Nandurbar Maharashtra India

Abstract

Targeting drug delivery specifically to the colon has become increasingly crucial for treating various colonic diseases like colorectal cancer, amebiasis, ulcerative colitis, and Crohn’s disease. Numerous strategies have been developed for this purpose, including using enzymatically degradable polymers, employing prodrug-based approaches, coating drugs with polymers sensitive to time or pH changes, utilizing osmotically and pressure-controlled delivery systems. Polysaccharides activated by the colon’s physiological environment show significant potential as they offer enhanced site specificity and address therapeutic requirements effectively. However, delivery systems relying solely on a single polysaccharide often fail to ensure precise targeted release due to variations in pH and transit time among individuals and disease states. Traditional methods often result in premature drug release. To overcome these challenges, combining or chemically modifying polysaccharides has been explored, effectively mitigating the limitations associated with single polysaccharide use. This review explores emerging approaches in this field, reexamines current technologies, and outlines future developments.

Keywords: Colonic diseases, Targeted drug delivery, Enzymatically degradable polymers, Polysaccharides, Site specificity

[This article belongs to International Journal of Membranes(ijm)]

How to cite this article: Mr.Harshal K Patil. Comprehensive Overview of Carbohydrate Polymers. International Journal of Membranes. 2024; 01(01):-.
How to cite this URL: Mr.Harshal K Patil. Comprehensive Overview of Carbohydrate Polymers. International Journal of Membranes. 2024; 01(01):-. Available from: https://journals.stmjournals.com/ijm/article=2024/view=147177





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Regular Issue Subscription Review Article
Volume 01
Issue 01
Received May 10, 2024
Accepted May 19, 2024
Published May 21, 2024