Molecular Docking of Cocculus hirsutus Phytocompounds with the Selective DENV Virus Stereotypes

Year : 2023 | Volume : 01 | Issue : 01 | Page : 17-29
By

    Prabhuram K

  1. Shubham Wanarase

  1. Student, Department of Bioinformatics, Bionome, Karnataka, India
  2. Student, Department of Bioinformatics, Bionome, Karnataka, India

Abstract

Dengue is a tropical disease with a high infection rate worldwide. Though treatments are available for the symptoms, anti-dengue drugs are unavailable. To tackle this issue, the study aims to shortlist the potential phytocompounds from Cocculus hirsutus medicinal plant, prevalent in South and South East Asia. Using molecular docking and ADME analysis, two potential compounds possessing high drug-likeness are identified namely, Sinococuline and Morphinan.

Keywords: DENV, NS1, anti-dengue, molecular docking

[This article belongs to International Journal of Genetic Modifications and Recombinations(ijgmr)]

How to cite this article: Prabhuram K, Shubham Wanarase Molecular Docking of Cocculus hirsutus Phytocompounds with the Selective DENV Virus Stereotypes ijgmr 2023; 01:17-29
How to cite this URL: Prabhuram K, Shubham Wanarase Molecular Docking of Cocculus hirsutus Phytocompounds with the Selective DENV Virus Stereotypes ijgmr 2023 {cited 2023 May 20};01:17-29. Available from: https://journals.stmjournals.com/ijgmr/article=2023/view=111657

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Regular Issue Subscription Original Research
Volume 01
Issue 01
Received April 13, 2023
Accepted May 6, 2023
Published May 20, 2023