Nanotechnology-Enabled Biosensors for Early Disease Diagnosis and Personalized Healthcare Monitoring
Seethaladevi, 
Keywords
Nanotechnology, biosensors, early disease diagnosis, personalized healthcare monitoring, nanomaterials, biomarkers, sensitivity, selectivity.
Abstract
Nanotechnology has revolutionized the field of biosensors, enabling early disease diagnosis
and personalized healthcare monitoring. Utilising the special qualities of
nanomaterials—such as their high surface-to-volume ratio, remarkable electrical and optical
capabilities, and customised surface chemistry—nanotechnology-enabled biosensors create
extremely sensitive and focused diagnostic instruments. With previously unheard-of
sensitivity and accuracy, these biosensors are able to identify and measure a wide range of
biomarkers, such as proteins, nucleic acids, and tiny molecules.This paper provides a
comprehensive review of the latest advancements in nanotechnology-enabled biosensors,
their working principles, fabrication techniques, and applications in early disease diagnosis
and personalized healthcare monitoring. It also covers the difficulties and potential
developments in this quickly developing industry.
References
1.Gerdan, Zeynep, Yeseren Saylan, and Adil Denizli.(2024) “Biosensing Platforms for
Cardiac Biomarker Detection.” ACS omega 9.9 (2024): 9946-9960.
2.Parihar, Arpana, Kritika Gaur, and Raju Khan.(2024) “Rapid diagnostic assays for the
detection of Alzheimer’s and Parkinson’s diseases.” Smart Diagnostics for Neurodegenerative
Disorders. Academic Press, 2024. 221-250.
3.Eswaran, U., Eswaran, V., Murali, K., and Eswaran, V.(2023a) “Recent Developments in
Microcantilever-based Biosensors for Detection of Pathogens and Toxins,” International
Journal of Applied Nanotechnology, Publisher: STM Journals, Year: 2023.
4.Manoharan, Arun Kumar, et al.(2024) “Recent Advances in Two-Dimensional
Nanomaterials for Healthcare Monitoring.” ACS sensors (2024).
5.Eswaran, U., Eswaran, V., Murali, K., and Eswaran, V.(2023c) “Fusion of Intelligence:
Biosensors and AI in the Medical Landscape,” Journal of Artificial Intelligence Research &
Advances, Publisher: STM Journals, Year: 2023.
6.Eswaran, U., Eswaran, V., Murali, K., and Eswaran, V. (2023d). A Novel Wearable
Biosensor for Real-Time Alcohol Detection. i-manager’s Journal on Electronics Engineering,
13(4), 48-55.
7.Eswaran, U et al.,(2018) “Design and Analysis of High Sensitive Microcantilever Based
Biosensor for CA 15-3 biomarker detection,” Journal of Applied Science and Computations,
2018, 682-698.
8.Eswaran U, ESWARAN V, MURALI K, ESWARAN V. FLEXING FRONTIERS:
PIONEERING ADVANCES IN BIOSENSORS FOR INSTANT HEALTH INSIGHTS. i-
manager’s Journal on Electronics Engineering. 2023 Oct 1;14(1).
9.Eswaran, U., Eswaran, V., Murali, K., and Eswaran, V. (2024). Elevating Healthcare: The
Synergy of AI and Biosensors in Disease Management. i-manager’s Journal on Artificial
Intelligence & Machine Learning, 2(1), 73-79.
10.Eswaran, U., Eswaran, V., Murali, K., and Eswaran, V. (2023f). Machine Learning for
Detecting Substance use Behaviors from Wearable Biosensor Data Streams: A Survey and
Outlook for 5G/6G Connectivity. i-manager’s Journal on Software Engineering, 18(1), 56-
63.
11.Eswaran, U et al.,(2012) “Design and development of Software reference models for
Biosensors,” International Conference on Engineering and Technology, 2012, 343-350, ISBN:
978-1-4675-1449.
12.Maghiani, I., et al.(2024) “Application of NiFe2O4 nanoparticles towards the detection of
ovarian cancer marker.” Materials Research Bulletin 177 (2024): 112835.
13.Eswaran, U., Eswaran, V., Murali, K., and Eswaran, V.(2023b) “Integrating
Nanotechnology And Biosensors For Enhanced Disease Detection,” Journal of NanoScience
Nanoengineering & Application, Publisher: STM Journals, Year: 2023.
14.Oruganti, Srividya, and Seshadri Reddy Ankireddy (2024). “Novel nanotechnology
approaches for the detection of human viral pathogens: a comprehensive review.” Recent
Developments in Nanomaterial-based Sensing of Human Pathogens (2024): 153-184.
15.John, Greeshma Sara, et al.(2024) “Recent Advances in Carbon Nanotube-Based
Electrochemical and Optical Biosensors.” Carbon Nanotubes for Biomedical Applications and
Healthcare (2024): 147-166.
16.Sakore, Preeti, et al.(2024) “The theranostic potential of green nanotechnology-enabled
gold nanoparticles in cancer: A paradigm shift on diagnosis and treatment
approaches.” Results in Chemistry 7 (2024): 101264.
17.Abdel-Karim, Randa.(2024) “Nanotechnology-Enabled Biosensors: A Review of
Fundamentals, Materials, Applications, Challenges, and Future Scope.” Biomedical Materials
& Devices (2024): 1-19.