Nada Mohammed Reda,
Hawraa Ghassan Hussein Salim,
awther Kadhem Abd-Alrudhe Hassan,
Suhair Abdulkareem Habeeb,
- Assistant Professor Department of Biology, College of Education for Girls, Kufa University Iraq
- Assistant Professor Department of Biology, College of Education for Girls, Kufa University Iraq
- Assistant Professor Department of Biology, College of Education for Girls, Kufa University Iraq
- Assistant Professor Department of Biology, College of Education for Girls, Kufa University Iraq
Abstract
Plant extracts are among the methods that have been used since ancient times in alternative medicine and are still developing until recently with the progress of science and modern technologies. These materials can be used in the composition of many pharmaceutical drugs. The current research aimed to evaluate the inhibitory effect of alcoholic and hot aqueous extract of the roots of Costus specious on some gram-positive and gram-negative bacteria (Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia) that cause many diseases to find new factors have antimicrobial action against pathogenic microorganisms. Diagnosed bacterial isolates were obtained from several places, including postgraduate students in the Department of Biology, the Central Health Laboratory, and the Al-Ghari Al-Ahly Laboratory. An alcoholic extract and hot water were also prepared, and the effect of the two extracts on the previously mentioned bacteria was tested using the well diffusion method. Where the results indicated that the alcoholic extract of the roots of the Indian Costus plant was more effective in inhibiting the growth of the tested bacteria compared to the hot aqueous extract, which did not show any inhibitory activity for the growth of bacteria and in all concentrations used (150, 200 250,300) mg/ml. It was also noted that the inhibitory effect of the extract increased with increasing concentration. Gram-positive bacteria were the most sensitive to the alcoholic extract and to all concentrations used, as Staphylococcus aureus showed a synergistic effect that inhibited growth in most of the plate, while Pseudomonas aeruginosa and Klebsiella pneumonia were the least sensitive to the extract. Thus, it can be concluded that the Indian costus plant has an important role as an inhibit to many bacterial species that threaten human life, and it can be an alternative to antibiotics. It can also be used as a food preservative instead of chemicals that pose a threat to human life.
Keywords: Enterococcus faecalis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumonia
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Research & Reviews : A Journal of Life Sciences
Volume | |
Received | August 6, 2024 |
Accepted | August 27, 2024 |
Published | August 31, 2024 |