Total Articles : 11
The Redox Rheostat: A Review on Targeting the Oxidative Stress-to- Cell Death Continuum for Therapeutic Gain
Abstract: For a long time, oxidative stress was cast as a plain villain, something to be pushed down with antioxidants wherever it appeared. That view has changed. Reactive oxygen species (ROS) do real work in the cell. At low concentrations, molecules such as …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
The Cellular Architecture of Feed Efficiency: Can Single-Cell Multi-Omics, Spatial Metabolomics, and Nutrient-Flux Mapping Reveal Hidden Metabolic Specialization across Intestinal, Hepatic, and Skeletal-Muscle Cell Populations in Poultry?
Abstract: Feed efficiency in poultry emerges from complex interactions among nutrient absorption, metabolic transformation, cellular energy expenditure, and productive tissue accretion. However, conventional whole-organ and bulk-tissue approaches inadequately …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Unveiling Therapeutic Targets in COPD: A Synergistic Approach Using Network Pharmacology and Molecular Docking
Abstract: COPD is a chronic lung disease that affects a large number of people worldwide and is a cause of death. Despite existing medications, effective therapies with fewer side effects is still needed. The use of herbal medicine, especially Zataria …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Mass Spectrometry–Based Phosphoproteomic Markers to Predict Kinase Inhibitor Response in Solid Tumors
Abstract: Mass spectrometry-based phosphoproteomics has emerged as a powerful tool for predicting kinase inhibitor responses in solid tumors, offering direct functional insights into signaling pathways that surpass traditional genomic profiling by capturing …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Exploring Oroxylum indicum Phytochemicals as VEGFR-2 Inhibitors: A Molecular Docking Approach for Cancer Management
Abstract: Cancer is still a major health problem around the world and is one of the top causes of death. A protein called VEGFR-2 (vascular endothelial growth factor receptor 2) is important because it helps blood vessels grow by supporting the survival, …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Molecular Docking Studies of Nyctanthes arbor-tristis Phytochemicals for Targeting TNF Receptor in Arthritis
Abstract: Rheumatoid Arthritis is an autoimmune disorder which results in inflammation. Tumor necrosis factor-alpha (TNF-α) is responsible for the progression of inflammatory arthritis by promoting immune cell activation and cytokine release. The present study …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Molecular Docking Analysis of Phytocompounds from Ficus hispida Aagainst Epidermal Growth Factor Receptor Kinase Domain
Abstract: The Epidermal Growth Factor Receptor (EGFR) kinase domain plays a key role in cancer, as it promotes tumour growth and helps cancer cells survive, making it an important focus for developing treatments. Through comprehensive computational analysis, …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Molecular Docking Analysis of Berberis aristata phytocompounds as Potential Growth Factor Receptor Blockers in Cancer Therapy
Abstract: Middle-aged and older women are susceptible to breast cancer (BC), a potentially fatal condition. When breast cancer is diagnosed, the median age is 62. Breast cancer diagnoses in women under 45 are comparatively uncommon, whereas the bulk of breast …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]
Drug Repurposing of Anticancer Agents JP-8g and REDX05358 Against the Target Protein Plectin 1a in Epidemolysis Bullosa Simplex with Muscular Dystrophy (EBS-MD)
Abstract: Epidermolysis Bullosa Simplex with Muscle Dystrophy is a genetic disease affecting the skin and muscles which can be seen at birth or start at adulthood due to the mutation in the protein Plectin 1a (PLEC gene) causing skin blisters and muscle …
[This section belongs to International Journal of Cell Biology and Cellular Functions ]