Nabiel Salam,
Prof Dr Ravi Kumar Chittoria,
Padmalakshmi Bharati Mohan,
Kanav Gupta,
Jacob Antony Chakiath,
- Junior Resident Department of Orthopedic Surgery Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India
- Professor of Plastic Surgery & Registrar (Academic) Head of IT Wing and Telemedicine Department of Plastic Surgery & Telemedicine Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India
- Assistant Professor Department of plastic surgery Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India
- Senior Resident Department of Plastic Surgery Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India
- Senior Resident Department of Plastic Surgery Jawaharlal Institute of Postgraduate Medical Education and Research Pondicherry India
Abstract
Advancements in wound healing have incorporated tissue regeneration therapy as a crucial tool for managing both acute and chronic wounds. Bio constructs designed to facilitate wound regeneration utilize natural, artificial, or hybrid materials, collectively referred to as regeneration scaffolds. The components of regeneration scaffolds play a crucial role in enhancing the skin’s natural self-renewal abilities and accelerating the healing process. These scaffolds are designed to provide essential growth factors and stem cells that stimulate cell proliferation and tissue repair. By creating an optimal environment for cellular activities, they help in quicker wound healing and tissue regeneration, leading to improved recovery outcomes. This advanced approach not only supports the body’s inherent healing mechanisms but also ensures more efficient and effective restoration of damaged skin. Scaffolds have played crucial roles in diverse medical and research contexts over an extended period. However, commercially available scaffolds are often prohibitively expensive, limiting their accessibility. To address this issue, an indigenous scaffold was developed using a combination of multiple components, including the amniotic membrane, collagen, and silicone. This new method aimed to produce a more affordable option without sacrificing standards of excellence. Through rigorous testing and evaluation, it was found that this indigenous scaffold performed on par with, and in some cases even surpassed, the commercially available options in terms of functionality and efficacy. This development not only offers a more affordable solution but also paves the way for wider use in medical and scientific fields.
Keywords: Regeneration scaffold; post burn raw area; dermal regeneration; regenerative therapy, indigenous scaffold, silicone, medical field
[This article belongs to Research & Reviews: A Journal of Health Professions(rrjohp)]
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Research & Reviews: A Journal of Health Professions
Volume | 14 |
Issue | 02 |
Received | May 27, 2024 |
Accepted | July 14, 2024 |
Published | August 14, 2024 |