Green Solvents in Synthesis of Schiff’s Base: A Comprehensive Review of Sustainable Approach

Open Access

Year : 2024 | Volume :11 | Issue : 03 | Page : –
By

Shashi V. Ranga,

Mansi Gandhi,

  1. Assistant Professor (chemistry) Govt. Engineering College, Valsad Gujarat India
  2. Research Scholar Gujarat Technological University Gujarat India

Abstract

The synthesis of Schiffs & bases is a fundamental process of organic synthesis that traditionally involves using hazardous organic solvents. These solvents pose significant risks to both the environment and human health due to their toxicity, volatility, and persistence in nature. These negative effects of organic solvents have led to the development of greener and more sustainable alternatives that aligns with the principles of Green Chemistry. This review paper aims to provide a comprehensive overview of the effectiveness of various green solvents such as water, ionic liquids and supercritical carbon dioxide, in promoting the condensation reaction between amines and aldehyde or ketones. It first discusses about the various traditional solvents used in synthesis of Schiff’s bases and their advantages and disadvantages. The paper then discuss about advantages, disadvantages and the challenges associated with the use of water, Ionic liquids and supercritical carbon dioxide, as solvent in Schiff’s base synthesis. Water, is highlighted for its non-toxic, non-flammable, and environmentally benign properties, leading to high yields of Schiff’s bases without the need for additional catalysts, as reported in number of research studies. Ionic liquids, characterized by their low volatility and tunable properties, are explored as versatile green solvents. Supercritical carbon dioxide (scCO 2 ) is presented as another promising green solvent since it is non-toxic, non-flammable, and can be easily removed from the reaction mixture by depressurization, leaving no solvent residues. Furthermore, these solvents can be designed to possess specific characteristics that enhance the reaction efficiency and selectivity. Additionally, this review highlights the importance of considering green chemistry principles in the synthesis of Schiffs & bases and emphasizes the potential of green solvents to revolutionize this field.

Keywords: Schiff’s base, green solvents, ionic liquids, supercritical carbon dioxide, sustainable synthesis

[This article belongs to Emerging Trends in Chemical Engineering(etce)]

How to cite this article: Shashi V. Ranga, Mansi Gandhi. Green Solvents in Synthesis of Schiff’s Base: A Comprehensive Review of Sustainable Approach. Emerging Trends in Chemical Engineering. 2024; 11(03):-.
How to cite this URL: Shashi V. Ranga, Mansi Gandhi. Green Solvents in Synthesis of Schiff’s Base: A Comprehensive Review of Sustainable Approach. Emerging Trends in Chemical Engineering. 2024; 11(03):-. Available from: https://journals.stmjournals.com/etce/article=2024/view=160279

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Regular Issue Open Access Review Article
Volume 11
Issue 03
Received June 26, 2024
Accepted July 11, 2024
Published August 1, 2024
Views: 35

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