Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital

Year : 2024 | Volume :01 | Issue : 02 | Page : 18-25
By

Mahendra Singh Rathore,

Bhaktraj Singh Chauhan,

Udita Singh,

Nidhi Kaushal Karva,

Deepali Pathak,

  1. Principal, Department of Clinical Pharmacy, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
  2. Assistant Professor, Department of Pharmacy Practice, Bhupal Nobles College of Pharmacy, Udaipur, Rajasthan, India
  3. Clinical Process Associate, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
  4. Assistant Professor, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
  5. Drug Control Officer, Food Safety and Drug Control Organization, Udaipur, Rajasthan, India

Abstract

Context: Depression leads to more dysfunction and stress, which could affect the patient’s life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established.
Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence among pulmonary tuberculosis patients using Morisky Scale. Settings and Design: A cross-sectional study was conducted at tertiary care hospital in Udaipur, Rajasthan. Methods and Material: A cross-sectional study was conducted in a tertiary care hospital at Udaipur, Rajasthan, between October 2021- July 2022. The cross-sectional study was performed on people with active pulmonary tuberculosis of 18 years and above who are on anti-tuberculotic medications. Results: The subjects with a mean age of 80.07±17.33 had moderately severe depression, and 52.07±17.3 had severe depression as per the PHQ-9 score. Out of 53 males, 12 were severely depressed, and out of 39 females, 13 had depression. The influence of medication adherence on tuberculosis patients with depression showed a negative correlation i,e; (R= -762). The correlation findings were found to be significant (0.01). Our results were consistent with the expected hypothesis, and finally, a substantial interaction between tuberculosis patients and depression was observed. Conclusions: We noticed a significant association between pulmonary tuberculosis and depression. Also, the study interpreted that low medication adherence to anti-tuberculosis treatment may lead to severe depression.

Keywords: Tuberculosis, Depression, Medication Adherence, pulmonary tuberculosis, Major depressive disorder, Morisky Medication Adherence Scale, PHQ-9 Scale.

[This article belongs to International Journal of Pathogens(ijpg)]

How to cite this article: Mahendra Singh Rathore, Bhaktraj Singh Chauhan, Udita Singh, Nidhi Kaushal Karva, Deepali Pathak. Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital. International Journal of Pathogens. 2024; 01(02):18-25.
How to cite this URL: Mahendra Singh Rathore, Bhaktraj Singh Chauhan, Udita Singh, Nidhi Kaushal Karva, Deepali Pathak. Assessment of exacerbation of Depression in pulmonary tuberculosis patients by using PHQ-9 scale at Tertiary Care Hospital. International Journal of Pathogens. 2024; 01(02):18-25. Available from: https://journals.stmjournals.com/ijpg/article=2024/view=160236

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Regular Issue Subscription Original Research
Volume 01
Issue 02
Received June 19, 2024
Accepted July 5, 2024
Published July 31, 2024
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