Novel Nanotherapeutics for the Management of Diabetes

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Year : July 31, 2024 at 12:38 pm | [if 1553 equals=””] Volume :26 [else] Volume :26[/if 1553] | [if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] : 01 | Page : 46-67

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Rachana R,

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  1. Professor Department of Biotechnology, Jaypee Institute of Information Technology, Sector 62, NOIDA,India Uttar Pradesh India

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Abstract

nDiabetes is a severe chronic disorder with hyperglycemia, either due to dysfunctional pancreas
(Type I) or due to malfunctioned glucose utilizing entities like: liver, straight muscle or
adipocytes (Type II). Type 1 or Insulin-dependent/Juvenile diabetes and Type 2 Diabetes
Mellitus or Non-Insulin dependent/Adult-onset diabetes are the two broad classifications of
diabetes. In case of type 1 diabetes injectable insulin is the major form of medication given and
in case of Type 2 DM, α-glucosidase inhibitors, insulin sensitizers, SGLT2, insulin
secretagogues, biguanides, amylin antagonists, incretin mimetics, and inhibitors are majorly
used. Monotherapy and combination therapies are the preferred therapies to manage type 2
diabetes nowadays. Conventional antidiabetic drugs majorly lack cost effectiveness and have
side effects and so the world is now again shifting towards using traditional medications based
on natural products. Traditional drugs also have many complexities such as: low bioavailability,
small shelf life and non-targetability. To address such issues in both the cases of modern day
medicine or natural products based medicines: nanotechnology-based drug delivery systems are
being devised. The present review introduces the basics of diabetes and discusses
nanotechnology-based drug delivery for diabetic patients, majorly for natural products based
antidiabetic.

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Keywords: Diabetes, Nano therapeutics, Nanotechnology, Phytotherapeutics

n[if 424 equals=”Regular Issue”][This article belongs to Nano Trends-A Journal of Nano Technology & Its Applications(nts)]

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[/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in Nano Trends-A Journal of Nano Technology & Its Applications(nts)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

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How to cite this article: Rachana R. Novel Nanotherapeutics for the Management of Diabetes. Nano Trends-A Journal of Nano Technology & Its Applications. July 31, 2024; 26(01):46-67.

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How to cite this URL: Rachana R. Novel Nanotherapeutics for the Management of Diabetes. Nano Trends-A Journal of Nano Technology & Its Applications. July 31, 2024; 26(01):46-67. Available from: https://journals.stmjournals.com/nts/article=July 31, 2024/view=0

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Volume 26
[if 424 equals=”Regular Issue”]Issue[/if 424][if 424 equals=”Special Issue”]Special Issue[/if 424] [if 424 equals=”Conference”][/if 424] 01
Received July 3, 2024
Accepted July 26, 2024
Published July 31, 2024

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