Sushil Nepali,
Ravi Kumar Chittoria,
Jacob Antony Chakiath,
Kanav Gupta,
Abstract
A Growth Factor represents a naturally-occurring compound with the remarkable ability to incite
cellular growth, proliferation, and differentiation. Typically manifesting as either a protein or a steroid
hormone, these factors wield significant influence over an array of cellular activities. Their pivotal role
lies in the regulation of diverse cellular processes, often serving as catalysts for cell specialization and
maturation, a characteristic that distinguishes them from one another. For instance, bone morphogenic
proteins are renowned for their capacity to ignite the differentiation of bone cells, whereas fibroblast
growth factors and vascular endothelial growth factors are instrumental in orchestrating the
differentiation of blood vessels, a phenomenon known as angiogenesis. These Growth Factors represent
critical signaling molecules that orchestrate the intricate dance of cellular behavior, ensuring the
proper functioning and development of biological systems. Their effects span a spectrum, from
promoting cell division to guiding cells towards specific fates. In essence, they act as molecular
messengers, relaying instructions that shape the landscape of cellular growth and development. The
significance of Growth Factors extends beyond individual cells to encompass broader physiological
processes, such as tissue repair, embryonic development, and immune response modulation. Their
intricate interplay with other molecular players within the cellular milieu underscores their
indispensability in maintaining the delicate balance of biological function. Thus, understanding the
mechanisms underlying Growth Factor activity holds profound implications for fields ranging from
regenerative medicine to cancer therapeutics, offering tantalizing avenues for intervention and
manipulation in the pursuit of improved health outcomes.
Keywords: Wound healing, recombinant human epidermal growth factor, angiogenesis, cytokines
[This article belongs to Research & Reviews: A Journal of Bioinformatics(rrjobi)]
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| Volume | 11 |
| Issue | 02 |
| Received | May 3, 2024 |
| Accepted | May 7, 2024 |
| Published | July 20, 2024 |