The Dual Crisis: Antibiotic Resistance and the Discovery Void – A Review of Novel Therapeutic Strategies and Non-Traditional Approaches
The global rise of antimicrobial resistance (AMR) has emerged as one of the most critical public health challenges of the 21st century, threatening to undermine decades of therapeutic success and rendering conventional antibiotic regimens increasingly ineffective.
Antibiotic resistance; antimicrobial resistance (AMR); discovery void; novel therapeutics; non-traditional antimicrobials; bacteriophage therapy; antimicrobial peptides; host-directed therapy; microbiome modulation; anti-virulence strategies; CRISPR antimicrobials; nanoparticle therapeutics; synthetic biology; drug discovery.