Total Articles : 10
Monoclonal Antibodies in Next Generation Animal Nutrition: Mapping Nutrient Immune Interaction Networks in Livestock Systems
Abstract: Sustainable livestock production is increasingly constrained by disease pressure, antimicrobial resistance, and declining feed efficiency under intensifying environmental stressors. Conventional nutritional strategies, while essential, remain …
[This section belongs to International Journal of Molecular Biotechnological Research ]
Integrative Structural-Functional Genomics of Fc and Fab: Precision Models for Monoclonal Antibody Stability and Anti-Aggregation Engineering
Abstract: Monoclonal antibodies (mAbs) represent the cornerstone of biotherapeutics, yet aggregation propensity compromises up to 50% of candidates during development, driven by Fab hypervariability and Fc vulnerabilities.(1,2) This review integrates …
[This section belongs to International Journal of Molecular Biotechnological Research ]
The Next Era of Molecular Biotechnology: Beyond DNA
Abstract: Molecular biotechnology has advanced much beyond conventional DNA manipulation, into a phase characterised by precision, integration, and invention. This article examines the evolving domain of next-generation biotechnological instruments, …
[This section belongs to International Journal of Molecular Biotechnological Research ]
Pharmacoepigenomics of Replication Timing: How Anti- Cancer Drugs Reshape Chromatin Domains and Mutational Landscapes.
Abstract: DNA replication timing serves as a fundamental epigenetic feature that organizes genome function during the cell cycle (3), while anti-cancer drugs profoundly alter this process to disrupt tumor growth(4). These agents target chromatin architecture, …
[This section belongs to International Journal of Molecular Biotechnological Research ]
REVIEW OF PHARMACOEPIGENETICS: BRIDGING EPIGENETICS AND PERSONALIZED MEDICINE
Abstract: Pharmacoepigenetics is an emerging field that explores how alterations in gene expression, independent of DNA sequence changes, influence individual responses to drugs. Unlike pharmacogenetics, which focuses primarily on genetic variation, …
[This section belongs to International Journal of Molecular Biotechnological Research ]
Challenges of Upgrading Local Cattle with Exotic Breeds: Genetic, Environmental, Economic, and Sustainability Trade-offs
Abstract: The practice of upgrading local cattle with exotic breeds has gained popularity as a strategy to enhance milk and meat production. While this approach holds potential for improving productivity, it also presents a range of challenges that need …
[This section belongs to International Journal of Molecular Biotechnological Research ]
In silico analysis of Abrus precatorius L. as a potential agonist of PPARĪ³ : A novel approach to the treatment of diabetes
Abstract: Diabetes mellitus is a chronic disorder that is characterized by a lack of insulin secretion by the pancreas or a defect in insulin action, or both. If diabetes is not controlled, over time it can cause damage to blood vessels and nerves, leading to …
[This section belongs to International Journal of Molecular Biotechnological Research ]
Exploring Abies grandis phytocompounds potential by in silico analysis targeting on the 5P9J Protein
Abstract: Blood Cancer, also popular with name āHematologic cancerā have variety of types: Leukaemia, Lymphoma, Myeloma, uncontrolled multiplication of blood cells mainly affecting to bone marrow and blood cells (White Blood Cells). Lymphoma, originating from …
[This section belongs to International Journal of Molecular Biotechnological Research ]
In silico Molecular Docking Analysis of Stephania glabra phytocompounds Targeting Thymidylate Kinase for potential Antituberculosis Activity
Abstract: Tuberculosis (TB) is an infectious disease caused by the bacteria Mycobacterium tuberculosis. It mainly affects the lungs and spreads through the air when a person with active TB in their lungs coughs, sneezes, or spits. This study investigates …
[This section belongs to International Journal of Molecular Biotechnological Research ]
Non-Enzymatic Glycation in Alzheimerās and Parkinsonās disease: A Molecular Approach to Pathology and Recent Advances
Abstract: Non-enzymatic glycation, a biochemical process by which reducing sugars spontaneously bind to proteins, leads to the formation of advanced glycation end-products (AGEs), which have emerged as critical contributors to the pathogenesis of several …
[This section belongs to International Journal of Molecular Biotechnological Research ]