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Research & Reviews : A Journal of Immunology Cover

Research & Reviews : A Journal of Immunology

E-ISSN: 2277-6206 | P-ISSN: 2349-1280 | Peer-Reviewed Journal (Refereed Journal) | Hybrid Open Access

About the Journal

Research and Reviews : A Journal of Immunology [2277-6206(e)] is a peer-reviewed hybrid open access journal launched in 2011 and focused on the rapid publication of fundamental research papers on all areas concerning various current and forthcoming radical new health professions across the globe due to cutting edge advancements in healthcare.

Focus & Scope

    • Innate Immunity and Inflammation: Pattern recognition receptors, pathogen-associated molecular patterns, phagocytosis, complement, neutrophils, macrophages, dendritic cells, natural killer cells, mast cells, innate lymphoid cells, cytokines and chemokines, epithelial barriers.
    • Adaptive Immunity: B and T lymphocytes, helper and memory T cells, cytotoxicity, antibody diversity, antigen receptors, MHC proteins, immunity to infection, immune-mediated inflammation.
    • Immune Regulation: Activation and suppression of immune cells, cytokine signaling, negative regulation and tolerance, neuroendocrine and glucocorticoid control of immunity, reactive oxygen species, immune homeostasis.
    • Molecular and Structural Immunology: Induction and termination of immune responses, structure of immune receptors, Toll-like and RIG-I-like receptors, inflammasomes and cGAS, NF-ÎşB and interferon signaling, structural biology of antigen presentation, pathogen immune escape, immune system evolution.
    • Developmental Immunology: Hematopoietic precursor cells, thymus and primary lymphoid organs, lymphocyte development, neonatal and pediatric immunity, maternal influences, placental development, immune aging.
    • Immunogenetics and Immune Omics: Genetic control of immune responses, MHC haplotypes, genome-wide association studies, quantitative trait loci, next-generation sequencing, CRISPR, single-cell transcriptomics, immunoproteomics, immune metabolomics, immune bioinformatics.
    • Allergies and Hypersensitivity: IgE-mediated, antibody-dependent, immune complex, and delayed-type hypersensitivity, allergens, histamine and prostaglandins, asthma, allergic rhinitis, angioedema, contact dermatitis, serum sickness, allergen-specific immunotherapy.
    • Autoimmunity and Immunodeficiency Diseases: Type 1 diabetes, celiac disease, Graves’ and Addison’s disease, systemic lupus erythematosus, autoimmune cytopenias, APECED and IPEX syndromes, SCID, CVID, Wiskott-Aldrich syndrome, complement disorders, secondary immunodeficiency, immunoglobulin replacement therapy.
    • Clinical Immunology: Diagnosis, prognosis, and treatment of immune-mediated disease, inborn errors of immunity, genotype–phenotype correlation, clinical laboratory immunology, HIV, immunodermatology.
    • Mucosal Immunology: Gastrointestinal, pulmonary, nasopharyngeal, oral, ocular, and genitourinary immunity, mucosa- and gut-associated lymphoid tissue, inflammatory bowel disease, food allergy.
    • Neuroimmunology: Neuroinflammation, immunity in neurodegenerative and psychiatric disease, CNS barriers and lymphatics, gut microbiome–brain interactions, autoimmune and paraneoplastic neurological disorders, Lambert-Eaton myasthenic syndrome, stiff person syndrome.
    • Reproductive Immunology: Immunology of implantation, placentation, pregnancy, and parturition, uterine natural killer cells, Th1/Th2 balance, fertility and recurrent pregnancy loss, endometriosis, immunocontraception, reproductive tract infections and cancers.
    • Transplantation: Histocompatibility, alloimmune recognition, graft rejection and survival, immunosuppressive pharmacology, hematopoietic stem cell transplantation, xenotransplantation, ethical issues in transplantation.
    • Tumor Immunology: Tumor microenvironment, anti-tumor immunity, CD8+ cytotoxic T cells, tumor immune contexture, apoptotic signaling, tumor immune evasion.
    • Immunotherapy and Vaccines: Immune checkpoint inhibitors, adoptive cell therapy, tumor-infiltrating lymphocytes, CAR T cells, therapeutic monoclonal antibodies, interferons and interleukins, BCG, cancer and preventive vaccines, vaccine manufacturing, safety, policy, and ethics.
    • Synthetic Immunity and Immunoengineering: Engineered immune cells, synthetic Notch receptors, immunomodulatory and biomimetic biomaterials, nanoparticle vaccines, immune cell manufacturing, bioelectronic devices, image-guided immunotherapies.
    • Immunohistology and Immunotechniques: Immunohistochemistry, immunofluorescence, diagnostic IHC markers, in situ hybridization, ELISA, ELISpot, western blotting, immunoprecipitation, radioimmunoassay, immunodiffusion, immunoelectrophoresis, agglutination, immunonephelometry, immunohematology.

Keywords

Innate immunity, Adaptive immunity, Cytokine signaling, Autoimmune diseases, Primary immunodeficiency, Hypersensitivity, Cancer immunotherapy, CAR T-cell therapy, Vaccine development, Immunohistochemistry

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