International Journal of Toxins and Toxics

International Journal of Toxins and Toxics [3048-507X(e)] is a peer-reviewed open-access journal launched in 2024 that aims to publish high-quality research articles and reviews related to all aspects of toxicology.

The Journal welcomes original research articles, reviews, and short communications from all parts of the world. All submitted manuscripts are peer-reviewed by experts in the field and accepted for publication based on their scientific quality, originality, and relevance to the field of toxicology.

The target audience for IJT includes toxicologists, environmental scientists, occupational health professionals, pharmacologists, regulatory agencies, and other researchers and professionals interested in toxicology and related fields. The ultimate goal of the journal is to advance knowledge and understanding of toxicology, microbiology, environmental science, toxicology, food science, pharmacology, and public health and to promote the development of safer and more effective strategies for protecting human health and the environment.

Focus and Scope:

Toxics

• Mechanisms of toxicity: Toxic substances, Molecular mechanisms, Cellular mechanisms, Biochemical mechanisms, Gene expression, Protein synthesis, Cellular signaling pathways, Oxidative stress, Apoptosis, Inflammation, DNA damage, Carcinogenesis, Epigenetics, Metabolism, Mitochondria dysfunction, Endoplasmic reticulum stress, Autophagy, Immune response, Neurotoxicity, Reproductive toxicity.
• Environmental toxicology: Environmental pollutants, Ecosystems, Wildlife, Natural resources, Air pollution, Water pollution, Soil pollution, Hazardous waste, Heavy metals, Pesticides, Persistent organic pollutants, Endocrine disruptors, Climate change, Ecotoxicology, Bioaccumulation, Biomagnification, Ecological risk assessment, Environmental monitoring, Biodiversity, Habitat destruction.
• Occupational toxicology: Occupational exposure, Workplace hazards, Occupational diseases, Risk assessment, Biomonitoring, Industrial chemicals, Solvents, Heavy metals, Dust and fibers, Noise, Heat stress, Radiation, Ergonomics, Respiratory protection, Personal protective equipment, Occupational health and safety, Carcinogens, Mutagens, Reproductive toxins, Skin irritants.
• Clinical toxicology: Poisoning, Drug overdose, Adverse drug reactions, Toxicological emergencies, Toxicokinetics, Toxicodynamics, Clinical toxicology testing, Analytical toxicology, Drug interactions, Therapeutic drug monitoring, Antidotes, Intensive care management, Poison control centers, Forensic toxicology, Alcohol and drug abuse, Toxicology screening, Drug abuse testing, Substance abuse treatment, Drug-related fatalities, Pharmacovigilance.
• Food and chemical safety: Food additives, Pesticides, Contaminants, Foodborne illness, Foodborne pathogens, Food safety regulations, Food labeling, Risk assessment, Chemical hazards, Environmental contaminants in food, Toxic metals in food, Food packaging materials, Food allergy, Food intolerance, Hazard analysis and critical control points (HACCP), Good manufacturing practices (GMP), Quality assurance, Chemical testing of food, Chemical analysis, Chemical exposure.
• Toxicology of natural products: Herbal medicines, Traditional medicines, Natural toxins, Plant toxins, Mushroom toxins, Marine toxins, Venoms, Poisons, Alkaloids, Glycosides, Terpenoids, Flavonoids, Phenols, Essential oils, Secondary metabolites, Toxicity assessment, Pharmacology, Pharmacokinetics, Drug interactions, Adverse effects.
• Toxicogenomics and epigenetics: Gene expression, Gene regulation, DNA damage, Mutagenesis, Genotoxicity, Epigenetic modifications, DNA methylation, Histone modification, Non-coding RNA, MicroRNAs, Long non-coding RNAs, Transcriptomics, Proteomics, Metabolomics, Omics technologies, Systems biology, Bioinformatics, Toxicity pathways, Mode of action, Biomarkers.

Toxins

• Toxin production by microorganisms, plants, and animals: Toxin production, Microbial toxins, Mycotoxins, Bacterial toxins, Virulence factors, Plant toxins, Plant defense mechanisms, Allelochemicals, Phytoalexins, Secondary metabolites, Animal toxins, Venomous animals, Poisonous animals, Toxin biosynthesis, Toxin regulation, Toxin expression, Toxin secretion, Toxin purification, Toxin characterization, Toxin structure-function relationships.
• Toxicity mechanisms and toxicokinetics of toxins: Toxicity, Toxicology, Mechanisms of toxicity, Target organ toxicity, Adverse effects, Cell toxicity, Cellular response, Molecular toxicity, Metabolic activation, Reactive metabolites, Oxidative stress, DNA damage, Genotoxicity, Carcinogenesis, Apoptosis, Necrosis, Immune toxicity, Neurotoxicity, Endocrine toxicity, Toxicokinetics, Absorption, Distribution, Metabolism, Elimination, Bioaccumulation, Biomarkers of toxicity.
• Toxicological effects of environmental toxins on human and animal health: Environmental toxins, Pollution, Chemical exposure, Xenobiotics, Pesticides, Heavy metals, Persistent organic pollutants (POPs), Endocrine disruptors, Carcinogens, Neurotoxins, Immunotoxicity, Reproductive toxicity, Teratogens, Mutagens, Ecotoxicology, Biomagnification, Bioaccumulation, Health effects, Toxicity testing, Risk assessment.
• Detection and identification of toxins using advanced analytical techniques, such as mass spectrometry, chromatography, and biosensors: Toxin detection, Toxin identification, Mass spectrometry, Liquid chromatography, Gas chromatography, Capillary electrophoresis, High-performance liquid chromatography (HPLC), Ultra-high-performance liquid chromatography (UHPLC), Tandem mass spectrometry (MS/MS), Matrix-assisted laser desorption/ionization (MALDI), Time-of-flight (TOF) mass spectrometry, Fourier-transform infrared (FTIR) spectroscopy, Biosensors, Enzyme-linked immunosorbent assay (ELISA), Surface plasmon resonance (SPR), Quartz crystal microbalance (QCM), Electrochemical sensors, Field-effect transistors (FET), Nanomaterials, Sample preparation.
• Bioremediation and detoxification of toxic compounds: Bioremediation, Detoxification, Microorganisms, Biodegradation, Biocatalysis, Enzymes, Bioreactors, Microbial consortia, Biostimulation, Bioaugmentation, Phytoremediation, Rhizoremediation, Mycoremediation, Biogeochemical cycles, Organic pollutants, Inorganic pollutants, Heavy metals, Biodegradable plastics, Biomass utilization, Genetically modified organisms (GMOs), Metabolic engineering, Environmental monitoring, Sustainable technology, Microbial ecology.
• Risk assessment and management of toxic substances: Risk assessment, Hazard assessment, Exposure assessment, Toxicity assessment, Risk management, Chemical Safety, Environmental risk assessme
  • Mechanisms of Toxicity: Molecular, cellular, and biochemical mechanisms, cellular signaling, oxidative stress, mitochondrial dysfunction, endoplasmic reticulum stress, autophagy, apoptosis and necrosis, inflammation, DNA damage, carcinogenesis, target organ toxicity, neurotoxicity, immunotoxicity, endocrine and reproductive toxicity.
  • Toxicokinetics and Metabolism: Absorption, distribution, metabolism, and elimination, metabolic activation, reactive metabolites, toxicodynamics, biomarkers of exposure and effect.
  • Environmental Toxicology: Air, water, and soil pollution, hazardous waste, heavy metals, pesticides, persistent organic pollutants, endocrine disruptors, ecotoxicology, bioaccumulation, biomagnification, wildlife and ecosystem effects, environmental monitoring.
  • Occupational Toxicology: Workplace exposure and biomonitoring, industrial chemicals and solvents, dusts and fibers, radiation, occupational carcinogens and mutagens, skin irritants, reproductive toxicants, occupational disease prevention.
  • Clinical and Forensic Toxicology: Poisoning, drug overdose, adverse drug reactions, toxicological emergencies, intensive care management, antidotes, poison control centers, analytical toxicology testing, therapeutic drug monitoring, drug abuse testing, drug-related fatalities, pharmacovigilance.
  • Food and Chemical Safety: Food additives, contaminants, toxic metals in food, pesticide residues, migration from packaging materials, foodborne hazards, food allergy and intolerance, chemical analysis of food, chemical exposure assessment.
  • Toxicology of Natural Products: Herbal and traditional medicines, plant, mushroom, and marine toxins, alkaloids, glycosides, terpenoids, phenols, essential oils, toxicity assessment of botanicals, herb–drug interactions.
  • Toxicogenomics and Epigenetics: Gene expression and regulation, mutagenesis, genotoxicity, DNA methylation, histone modification, microRNAs and long non-coding RNAs, transcriptomics, proteomics, metabolomics, systems biology, bioinformatics, toxicity pathways, mode of action.
  • Toxin Production by Microorganisms, Plants, and Animals: Microbial toxins, mycotoxins, bacterial toxins, virulence factors, plant toxins, allelochemicals, phytoalexins, venoms and animal poisons, toxin biosynthesis, regulation, secretion, purification, characterization, structure–function relationships.
  • Detection and Identification of Toxins: Mass spectrometry and tandem mass spectrometry, MALDI and time-of-flight analysis, liquid and gas chromatography, HPLC and UHPLC, capillary electrophoresis, FTIR spectroscopy, ELISA, biosensors, surface plasmon resonance, quartz crystal microbalance, electrochemical sensors, nanomaterials, sample preparation.
  • Bioremediation and Detoxification: Biodegradation, biocatalysis, microbial consortia, biostimulation, bioaugmentation, phytoremediation, rhizoremediation, mycoremediation, bioreactors, metabolic engineering, removal of organic and inorganic pollutants, microbial ecology.
  • Risk Assessment and Management: Hazard identification, exposure and dose–response assessment, human health and ecological risk assessment, threshold values and safety limits, uncertainty and data quality analysis, risk mitigation, risk communication and perception.
  • Regulatory Frameworks: Food, water, and environmental regulations, maximum residue limits, acceptable and tolerable daily intakes, international standards and guidance, surveillance programs, sampling plans, validated analytical methods, monitoring and enforcement.
  • Prevention and Treatment of Toxin-Related Disease: Antidote development, biologics, immunotherapy, toxin vaccines, nanoparticle drug delivery, gene therapy, pharmacogenomics and personalized treatment, computational modeling and machine learning for toxicity prediction, diagnostic tools.

  The journal publishes original research articles, reviews, and short communications. Occupational safety, food quality management, and ecology studies with no toxicological endpoint are out of scope. The journal serves toxicologists, environmental scientists, occupational health professionals, pharmacologists, food safety specialists, and regulatory agencies.

  Toxicology, Antidotes, Detoxification, Biologics, Nanoparticles, Drug delivery systems, Gene therapy, Immunotherapy, Vaccine development, Pharmacogenomics, Personalized medicine, Omics technologies, Proteomics, Metabolomics, Transcriptomics, Systems biology, Synthetic biology, Artificial intelligence, Machine learning, Computational modeling, Biomarkers, Diagnostic tools.