International Journal of Genetic Modifications and Recombinations

International Journal of Genetic Modifications and Recombinations [3048-5657]is a peer-reviewed hybrid open-access journal launched in 2023 that provides a medium for rapid publication of research and review articles that are original and can create an immediate impact on ongoing research. Journal includes site-specific recombination, recombination frequency, and recombination hotspots as the major topics. Articles included in the journal can be original research articles, review articles, or short communication.

The journal covers eight areas:

• Gene Patents: Diagnostic method patents, Functional use patents, Process patents, Composition of matter patents, Human gene patents, cDNA claims, Patentability criteria, Patent law and policy, Licensing and access, Ethical issues, Social implications, Economic impact of gene patenting.
• Genetic Diseases: Down syndrome, Fragile X syndrome, Klinefelter syndrome, Triple-X syndrome, Turner syndrome, Trisomy 18, Chromosomal abnormalities, Cytogenetics, Karyotyping, Epigenetics, Molecular genetics, Patterns of inheritance, Genomics, Genome analysis, Mitochondrial genetics, Behavioural genetics, Population genetics, Medical genetics.
• Genetic Engineering: Genome editing, CRISPR-Cas systems, Synthetic DNA components, Artificial chromosomes, Targeted epigenetic modification, Gene design, DNA isolation, Plant transformation, Transgenic crops, Herbicide and pest resistance traits, Biofortification, Phytoremediation, Post-harvest and shelf-life traits, Biosafety of engineered organisms.
• DNA Recombination: Homologous recombination, Site-specific recombination, Non-homologous end joining, Illegitimate recombination, Replicative recombination, Recombinase enzymes, DNA damage and repair, Chromatin and histone dynamics, Chromosome structure, Bacterial transformation, Transduction, Conjugation, Plasmid transfer.
• Restriction Endonucleases: Type I to Type IV restriction enzymes, Recognition sequences, Restriction–modification systems, DNA methylation, Methyltransferases, Restriction mapping, Plasmid vectors, Enzyme selection and cloning strategy, Ligation.
• Polymerase Chain Reaction: Conventional PCR, Reverse transcription PCR, Quantitative real-time PCR, Reverse transcriptase, Thermostable polymerases, Primer design, Buffer composition and cofactors, Magnesium optimisation, Thermal cycling conditions, Assay validation, Contamination control.
• Gene Cloning: Reproductive cloning, Therapeutic cloning, Somatic cell nuclear transfer, Expression vectors, Host systems, Recombinant protein production, Biopharmaceutical manufacture, Forensic DNA applications, Ethical considerations.
• Paratransgenesis: Vector-borne disease control, Symbiont engineering, Engineered microbiota, Gene drive systems, Population suppression and replacement, Malaria and dengue vectors, Containment and field release, Regulatory and biosafety frameworks.