Research & Reviews: A Journal of Drug Formulation, Development and Production

Research & Reviews: A Journal of Drug Formulation, Development and Production Research & Reviews: A Journal of Drug Formulation, Development, and Production [2394-1944(e)] is a peer-reviewed hybrid open-access journal launched in 2014 and focused on the publication of current Research/Review work carried out in the area of Drug Formulation, development, and production.

The journal welcomes contributions across the following topic areas:

• Drug Delivery Systems: oral and pulmonary delivery systems, nasal and intranasal delivery platforms, parenteral and intravenous delivery systems, transdermal and topical delivery systems, controlled-release and sustained-release formulations, microcapsules and microspheres, liposomes and lipid-based nanoparticles, vesicles and carrier systems, macromolecular conjugates and polymer-drug systems, antibody-targeted delivery, protein and peptide delivery systems, nucleic acid delivery and gene therapy, DNA and oligonucleotide delivery, siRNA and RNA interference therapeutics, nanomedicines and nanoparticulate systems, tissue engineering and regenerative delivery, image-guided drug therapy and theranostics, drug-device combination products, biocompatibility and biodegradation assessment, preclinical and clinical evaluation
• Drug Development & Product Development: medicinal and process chemistry, post-approval and post-marketing evaluation and surveillance, drug evaluation and regulatory approval processes, biologically active compounds in development, preclinical development studies and modeling, translational animal models and in vivo testing, emerging pharmaceutical technologies, pharmaceutical formulation development and optimization, drug repurposing and combination therapies, process development platforms and networks, regulatory science and compliance, manufacturing and scale-up, clinical translation and commercialization
• Drug Discovery & Target Validation: target identification and validation, phenotypic screening and target deconvolution, biochemical pathway analysis and mechanism elucidation, molecular and structure-based drug design, computer-aided drug discovery and in silico modeling, design and synthesis of novel biologically active compounds, structural and molecular biological studies, fragment-based drug discovery, high-throughput and medium-throughput screening approaches, three-dimensional cell cultures and organoid models, patient-derived tissues and models, in silico ADME-Tox predictions, bioavailability and permeability assessment, big data and machine learning applications, novel targets and therapeutic pathways, knowledge discovery and translation
• Pharmaceutical Formulation Research: quality by design and risk assessment, process optimization and scale-up, three-dimensional printing and novel manufacturing, inhalation therapy and aerosol formulation, aseptic processing and sterilization, bioavailability enhancement and permeation strategies, bioequivalence and comparative bioavailability, biosimilar development and characterization, biowaivers and bridging studies, topical formulations and dermatology delivery, galenic formulations and traditional dosage forms, injectable and infusion formulations, enteral and oral delivery, parenteral formulations and stability, dosage form design and selection, finished product characterization
• International Drug Regulatory Affairs: national and international regulatory guidelines, new drug application processes and submission, pharmacovigilance and post-market drug safety, regulatory compliance and quality oversight, legislative requirements and approval pathways, marketing authorization and regulatory strategy, good manufacturing practice standards, quality control and quality assurance protocols, regulatory dossier and drug master files, biopharmaceutical regulations, chemical and biologic regulatory requirements, import and export regulations, regulatory submissions and documentation, streamlined approval pathways
• Pharmacokinetics & Pharmacodynamics: drug absorption, distribution, metabolism, and excretion, kinetics of drug disposition in humans and animals, in vitro and in vivo modeling approaches, physiologically-based pharmacokinetic modeling, optimal design and exposure-response analysis, precision medicine and dose optimization, mechanism of drug action and efficacy, pharmacodynamic-pharmacokinetic relationships, toxicokinetics and toxicodynamics, mathematical modeling and simulation, population pharmacokinetics, scaling and allometry, dosage regimen design and evaluation
• Pharmaceutical Process Engineering: pharmaceutical manufacturing and production scale-up, supercritical fluid extraction and processing, chromatographic separation techniques, membrane separation and filtration, drying and moisture control technologies, sterilization and depyrogenation methods, genetic and cell engineering applications, enzyme and cell immobilization, bioreactor design and bioprocessing, process analytical technology and monitoring, quality control and statistical process control, pharmaceutical equipment and instrumentation, solid-liquid extraction and crystallization, evaporation and distillation, size reduction and classification, mixing and blending, solid dosage form processing, natural and herbal product processing, excipient development and characterization
• Pharmacognosy & Natural Products: natural product chemistry and isolation, bioassay and biological evaluation, structure-activity relationship studies, ethnopharmacology and traditional medicine, crude extract preparation and evaluation, essential oil composition and analysis, pure compound isolation and identification, structural elucidation and characterization, traditional pharmacy and herbal formulations, analytical method development and validation, mechanistic studies and mode of action, synthesis and chemical transformation, method and technique development, bioactive natural product evaluation
• Quality Control & Quality Assurance: ISO guidelines and standards compliance, NABL and laboratory accreditation, good manufacturing practice and manufacturing control, standard operating procedures and auditing, pharmaceutical quality systems and ICH Q10 compliance, HACCP and hazard analysis, good clinical and laboratory practices, pharmaceutical regulations and guidelines, quality management and quality policy, HPLC method development and validation, pharmaceutical validation protocols, drug quality standards and specifications, batch testing and release, raw material testing and acceptance, microbiological testing and sterility, product stability and shelf-life assessment, resampling and periodic testing, computerized systems and electronic records, quality documentation and traceability