Novel Inhalation Formulations Of Optimyxin

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Open Access Special Issue Topic

Novel inhalation formulations of optimyxin

Special Issue Description

Keywords

Manuscript Submission information

Published Articles

This special issue belongs to	Research & Reviews: A Journal of Pharmacology
Related section	NA
Deadline for Manuscript Submission	March 31st, 2023
Deadline for Publication	April 15, 2023

Special Issue Description

Dear Collegues,

Due to bacterial resistance and limited drug exposure at the infection site, intravenous and oral antibiotics are not usually effective for treating lung infections. A novel optimyxin combo medication has been created by Purdue University researchers to treat bacterial lung infections. Infections brought on by multi-drug resistant Gram-negative "superbugs" have frequently been treated with optimyxin as a last resort; nevertheless, inhaled optimyxin can be harmful to the lungs.

In comparison to the commonly used breathed optimyxin B and colistin, the novel formulations created by Purdue researchers create a potent therapeutic option with superior antibacterial killing and much-reduced toxicity. The Purdue dry powder formulation, which exhibits good stability and strong aerosolization capability, also shows potential as an inhaled treatment.

Keywords

Optimyxin
Dry powder inhaler
Klebsiella pneumonia
Enhanced efficacy
intravenous

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

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