Open Access   Special Issue    Topic

Novel inhalation formulations of optimyxin

  • Special Issue Description
  • Keywords
  • Manuscript Submission information
  • Published Articles
  •   This special issue belongs to

      Research & Reviews: A Journal of Pharmacology

      Related section

       NA

      Deadline for Manuscript Submission

      March 31st, 2023

      Deadline for Publication

      April 15, 2023

    Special Issue Description


    Dear Collegues,



    Due to bacterial resistance and limited drug exposure at the infection site, intravenous and oral antibiotics are not usually effective for treating lung infections. A novel optimyxin combo medication has been created by Purdue University researchers to treat bacterial lung infections. Infections brought on by multi-drug resistant Gram-negative "superbugs" have frequently been treated with optimyxin as a last resort; nevertheless, inhaled optimyxin can be harmful to the lungs.

    In comparison to the commonly used breathed optimyxin B and colistin, the novel formulations created by Purdue researchers create a potent therapeutic option with superior antibacterial killing and much-reduced toxicity. The Purdue dry powder formulation, which exhibits good stability and strong aerosolization capability, also shows potential as an inhaled treatment.

    Keywords

    Optimyxin
    Dry powder inhaler
    Klebsiella pneumonia
    Enhanced efficacy
    intravenous

    Manuscript Submission information


    Manuscripts should be submitted online by registering and logging in to this link. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed.
    Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent on email address:[email protected] for announcement on this website.
    Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

    Published articles

    "This special issue is now open for submission."