Open Access   Special Issue    Topic

Anti-Inflammatory drug delivery of Neurodegenerative disease

  • Special Issue Description
  • Keywords
  • Manuscript Submission information
  • Published Articles
  •   This special issue belongs to

      Trends in Drug Delivery Special Issues

      Related section

       NA

      Deadline for Manuscript Submission

      March 31st, 2023

      Deadline for Publication

      April 15, 2023

    Special Issue Description


    Dear Collegues,



    The immune system's biological response to an irritant is inflammation, which serves to defend living things from harm. However, excessive and unchecked inflammation is linked to several deadly Neurodegenerative disorders, such as Alzheimer's, Dementia, Huntington's disease, etc. A wide range of anti-inflammatory therapies are now available for the treatment and management of pertinent chronic diseases thanks to advances in our understanding of the inflammatory response. Despite these achievements, patients' clinical outcomes vary, and major side effects are frequently reported.

    Additionally, there are some restrictions for clinical anti-inflammatory therapies, including inadequate access to subcellular compartments, low bioavailability, off-target effects, and water insolubility. The rational design of inflammation-specific drug delivery systems (DDSs) offers tremendous potential for overcoming these difficulties. Additionally, compared to normal tissues, the pathological milieu associated with inflamed tissues (such as oxidative stress, an acidic pH, and overexpressed enzymes) offers crucial biochemical triggers for the triggered administration of anti-inflammatory drugs in a spatiotemporally regulated way. For the treatment of neuroinflammatory illnesses, we highlight current developments in the creation of anti-inflammatory DDSs with an integrated pathological inflammation-specific response.

    Keywords

    * Anti-Inflammatory agents
    * Drug delivery system
    * Inflammation
    * Stimuli-responsive polymers

    Manuscript Submission information


    Manuscripts should be submitted online by registering and logging in to this link. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed.
    Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent on email address:[email protected] for announcement on this website.
    Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page.

    Published articles

    "This special issue is now open for submission."