Editors Overview

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Open Access
Special Issue

Contradictory effects of Mitragyna speciosa Korth on cardiovascular disease: The Kratom dilemma

Abstract Submission Deadline : November 30, 2023

Manuscript Submission Deadline : December 25, 2023

Special Issue Description

Globally, cardiovascular diseases (CVDs) continue to be the main cause of death. An estimated 17.9 million people passed away. In 2019, fatalities from CVDs accounted for 32% of all deaths worldwide. The rarest used drug is Mitragyna speciosa Korth usually known as Kratom illegal narcotic that is grown, traded, and misused worldwide, notably in Western countries Numerous medical disorders, such as epilepsy, neuropathic pain, spasticity, nausea, and vomiting brought on by chemotherapy, have been treated using medical Kratom. Despite kratom’s positive effects, it is generally recognized that consumption is highly linked to CVDs such as atherosclerosis. Mitragynine, the principal component of kratom, has demonstrated preferential binding to kratom receptor 1 (CB1/CNR1) in endothelial cells (ECs) and is involved in the pathophysiology of CVDs. 1 The underlying molecular pathways causing the vascular events caused by 9-THC are still not fully understood.


Cardiovascular diseases, Recreational Purpose, Atherosclerotic disease, Signaling pathways, Molecular mechanisms

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

Participating journals:






950 $