International Journal of Cell Biology and Cellular Processes

Editors Overview

ijcbcp maintains an Editorial Board of practicing researchers from around the world, to ensure manuscripts are handled by editors who are experts in the field of study.

Open Access
Special Issue
Topic

A short review of cell genomics

Abstract Submission Deadline : November 30, 2024

Manuscript Submission Deadline : December 25, 2024

Special Issue Description

The little amounts of DNA and RNA present in a single cell may now be sequenced thanks to developments in whole-genome and whole-transcriptome amplification. This opens a window into the scope and nature of genomic and transcriptomic heterogeneity that occurs in both healthy development and sickness. Our ability to comprehend the scope of genomic, epigenomic and transcriptome variability that occurs throughout an individual organism’s lifetime will be revolutionized by single-cell techniques. Here, we review the important scientific and technical advances made, discuss the difficulties still facing us, and offer a preview of what the near future may hold. A key component of biology is the cell, which is where the genome’s blueprint is converted into biological form and function. Nearly all of our present knowledge of the genome and its control comes from population-level research, which often involves the mass analysis of thousands or millions of cells. Although helpful, the resulting analysis frequently ignores any variability that exists within the population of cells. Although it is generally believed that the genome is stable throughout normal development, there is a very small chance that a genetic mutation will occur with every cell cycle. Genomic heterogeneity, also known as somatic variation, will exist within the organism over a significant number of divisions. Recent investigations have found unexpectedly high levels of genomic variation in normal and diseased tissue, indicating higher rates of genetic damage than previously anticipated, even though such variation is at the core of many illnesses, including cancer. Still, little is understood about the nature and rate of DNA mutation, as well as how genetic makeup, lifestyle, and a variety of other factors affect these .

Keywords

DNA, Genetic mutation, Genetic makeup, Genomic, RNA

Manuscript Submission information

Manuscripts should be submitted online via the manuscript Engine. Once you register on APID, click here to go to the submission form. Manuscripts can be submitted until the deadline.
All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the email address:[email protected] for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a Double-blind peer-review process. A guide for authors and other relevant information for the submission of manuscripts is available on the Instructions for Authors page.

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