Detection and Classification of Alzheimer’s Disease Using Deep Learning Technique

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Year : 2025 | Volume :12 | Issue : 01 | Page : –
By
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T. Sharmila Devi,

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Dr. Sivakumar J.,

  1. Student, Department of Electronics and Communication Engineering, St. Joseph’s college of Engineering, Chennai, Tamil Nadu, India
  2. Student, Department of Electronics and Communication Engineering, St. Joseph’s college of Engineering, Chennai, Tamil Nadu, India

Abstract

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It is crucial that people with Alzheimer’s disease (AD) receive a proper diagnosis to begin preventative action before irreparable brain damage develops. Most people who suffer from Alzheimer’s disease (AD), a neurological condition that progresses, are older than 65. The area of interest (ROI) in the hippocampus has been extensively studied for several purposes, including neurological illness research, stress development monitoring, and memory function analysis. Moreover, a connection between Alzheimer’s disease and hippocampus volume shrinkage is shown. On the other hand, several biomarkers are used in the diagnosis of AD, such as tau, phosphorylated tau, amyloid beta (aβ42) protein, and hippocampus volume atrophy. Even though much recent research has used computers to diagnose AD, congenital findings with most of the machine learning strategies. information, such as MRI and PET imaging, we aim to improve diagnostic reliability. The model’s effectiveness had been assessed using standard metrics, and it achieved a high accuracy of 94.7% in classifying individuals into healthy, mild cognitive impairment (MCI), and Alzheimer’s sections. These findings highlight the possibility of deep learning as a tool for programmed and reliable Alzheimer’s recognition, offering significant advantages for clinical diagnostics. Alzheimer’s disease (AD) is a progressive neurodegenerative disease that primarily affects memory, cognition, and behaviour. Early and accurate detection of AD is essential for effective management and treatment planning. Deep learning, one of the most recent developments in artificial intelligence (AI), has the potential to completely transform medical diagnosis.

Keywords: Alzheimer’s disease, deep learning, Initial-stage detection and diagnosis, Sensor Research, Biomarkers, Machine Learning, magnetic resonance imaging

[This article belongs to Recent Trends in Sensor Research & Technology (rtsrt)]

How to cite this article:
T. Sharmila Devi, Dr. Sivakumar J.. Detection and Classification of Alzheimer’s Disease Using Deep Learning Technique. Recent Trends in Sensor Research & Technology. 2025; 12(01):-.
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T. Sharmila Devi, Dr. Sivakumar J.. Detection and Classification of Alzheimer’s Disease Using Deep Learning Technique. Recent Trends in Sensor Research & Technology. 2025; 12(01):-. Available from: https://journals.stmjournals.com/rtsrt/article=2025/view=0

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References

[1] F. ZHANG, Z. Li, B. Zhang, H. Du, B. Wang, X. Zhang,
Multimodal deep learning model for auxiliary diagnosis of Alzheimer disease, Neurocomputing 361(2019) 185-195.
[2] A. Mehmood, M. Maqsood, M. Bashir, Y. Shuyan, A deep Siamese convolution neural network for multi class classification of alzheimer disease, Brain Sci.10(2)(2020) 84.
[3] S.B. Shree A. Mehmood ,M. Maqsood , M. Bashir, Y .Shuyuan,A deep siamese convolution neural network for multi class classification of alzheimer disease,Brain Sci.10(2)(2020) 84.
[4] Y.Zhang , Z. Dong, P. Phillips,S.Wang,G. Ji, J.Yang,T.F.Yuan, Detection of subjects and brain regions related to Alzheimer’s disease using 3d MRI scans based on edge brain and machine learning,Front.Comput.Neurosci.9 (2015) 66.
[5] A. Abrol, M. Bhattarai, A. Fedorov, Y. Du, Plis, V. Calhoun, Initiative, et al,Deep residual learning for neuroimaging: An application to predict progression to alzheimer’s disease, J. Neurosci. Methods 108701(2020).
[6] M.A. Ebrahimighahnavieh, S. Luo, R. Chiong, Deep learning to detect Alzheimer’s disease from neuroimaging: A systematic literature review, Comput. Methods Programs Biomed. 187 (2020) 105242.
[7] M.P. Bhatkoti Pushkar, Early diagnosis of Alzheimer’s disease: A multi-class deep learning framework with modified k-sparse autoencoder classification.
[8] J. Islam, Y. Zhang, Brain mri analysis for alzheimer’s disease diagnosis using an ensemble system of deep convolutional neural networks, Brain informatics 5 (2) (2018) 1–14.
[9] M. Liu, F. Li, H. Yan, K. Wang, Y. Ma, L. Shen, M. Xu, A.D.N.
Initiative, et al, A multi-model deep convolutional neural network for automatic hippocampus segmentation and classification in Alzheimer’s disease, NeuroImage 208 (2020) 116459.
[10] S. Neffati, K. Ben Abdellafou, I. Jaffel, O. Taouali, K. Bouzrara, An improved machine learning technique based on downsized kpca for Alzheimer’s disease classification, Int. J. Imaging Syst. Technol. 29 (2) (2019) 121–131.
[11] S. Sarraf, G. Tofighi, Classification of Alzheimer’s disease using fMRI data and deep learning convolutional neural networks, arXiv preprint arXiv:1603.08631.
[12] Z. Cui, Z. Gao, J. Leng, T. Zhang, P. Quan, W. Zhao, Alzheimer’s disease diagnosis using enhanced inception network based on brain magnetic resonance image, in: 2019 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), IEEE, 2019, pp. 2324– 2330.
[13] E. Jabason, M.O. Ahmad, M. Swamy, Classification of Alzheimer’s disease from MRI data using an ensemble of hybrid deep convolutional neural networks, 2019 IEEE 62nd International Midwest Symposium on Circuits and Systems (MWSCAS), IEEE, 2019, pp. 481–484.
[14] M. Shahbaz, S. Ali, A. Guergachi, A. Niazi, A. Umer, Classification of Alzheimer’s disease using machine learning techniques, DATA (2019) 296–303
[15] Murugan S, Venkatesan C, Sumithra MG, Gao XZ, Elakkiya B, Akila M, Manoharan S (2021) DEMNET: a deep learning model for early


Regular Issue Subscription Review Article
Volume 12
Issue 01
Received 02/01/2025
Accepted 14/01/2025
Published 22/01/2025