Hyon Chol Jo,
Hak Song Jo,
Kum Hyok So,
- Researcher Department of Pathology, Pyongyang University of Medical Sciences Pyongyang Democratic People’s Republic of Korea
Abstract
Acute Rotavirus gastroenteritis in children, called “False Cholera”, is one of the children’s diarrheal diseases. Among symptomatic children with acute Rotavirus gastroenteritis, the chief clinical manifestations include diarrhoea, vomiting, fever and dehydration. We did research with such aims as follows to differentiate Acute Rotavirus Gastroenteritis in Children, with significant morbidity, from others in paediatric gastroenterology, and to introduce its etiological treatment. We selected 87 subjects who died from children’s diarrheal diseases and collected in several Province Paediatric Hospitals for a good decade. We did qualitative analysis by collecting faecal specimen from the patients died from gastroenteritis and by reacting it with the substrate for the Rotavirus Latex Agglutination Assay to divide patients into two groups: the patients positive for Rotavirus and the negative. We did some types of statistical analyses of the differences between diarrhoea and fever, properties of feces, clinical manifestation and morphology of intestinal mucosa in Rotavirus positive group and the negative. sections using general method with H&E, evaluated the necrotic defluxion of intestinal epithelium under ×100 light microscope (a score of 1; mild, 2; moderate, 3; severe) and observed the changes of villi and counted the infiltrated inflammatory cells in mucosa under ×400 light microscope morphologically. We conducted t-test on diarrhoea and fever and morphology of intestinal mucosa and performed χ2-test on properties of feces and clinical manifestation. Percentage changes according to clinical pathological findings of Acute Rotavirus Gastroenteritis in Children were clearly differ
Keywords: Acute rotavirus gastroenteritis, false cholera, children’s diarrheal diseases, clinical manifestations, paediatric gastroenterology, rotavirus latex agglutination assay.
[This article belongs to Research & Reviews : A Journal of Medical Science and Technology(rrjomst)]
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Research & Reviews : A Journal of Medical Science and Technology
| Volume | 13 |
| Issue | 02 |
| Received | January 30, 2024 |
| Accepted | July 5, 2024 |
| Published | August 13, 2024 |