Analysis of Bioinformatics Software Applied in Computer-Aided Drug Design

Year : 2024 | Volume : | : | Page : –
By

Satish kumar Yadav

Mohd. Wasiullah

Piyush Yadav

Vinay kumar Deepak

Divyansh Singh

  1. Associate Professor Dept. of Pharmacy, Prasad Institute of Technology Uttar Pradesh India
  2. Principal Dept. of Pharmacy, Prasad Institute of Technology Uttar Pradesh India
  3. Academic Head Dept. of Pharmacy, Prasad Institute of Technology Uttar Pradesh India
  4. Professor Dept. of Pharmacy, Prasad Institute of Technology Uttar Pradesh India
  5. Scholar Dept. of Pharmacy, Prasad Institute of Technology Uttar Pradesh India

Abstract

The integration of bioinformatic tools with computational methods has revolutionized the field of Computer-Aided Drug Design (CADD), enabling researchers to expedite the discovery and optimization of new therapeutics. This review provides an in-depth analysis of the bioinformatic tools utilized in CADD, encompassing molecular docking, molecular dynamics simulation, virtual screening, homology modeling, and molecular visualization. We go over the tenets, approaches, and uses of these instruments, emphasising their value in expediting the drug discovery process and tackling challenging biological issues. The convergence of bioinformatics and computational methods has ushered in a new era in drug discovery known as Computer-Aided Drug Design (CADD). This review explores the arsenal of bioinformatic tools utilized in CADD, encompassing molecular docking, molecular dynamics simulation, virtual screening, homology modeling, and molecular visualization. By elucidating the principles, methodologies, and applications of these tools, this review aims to provide a comprehensive understanding of their role in accelerating the drug discovery process. From target identification to lead optimization, bioinformatic tools play a pivotal role in expediting the identification and optimization of novel therapeutics, ultimately contributing to the advancement of human health.

Keywords: Computer-Aided Drug Design (CADD), Bioinformatic Tools, Molecular Docking, Molecular Dynamics Simulation, Virtual Screening, Homology Modeling, Molecular Visualization, Drug Discovery, Target Identification, Lead Optimization.

How to cite this article: Satish kumar Yadav, Mohd. Wasiullah, Piyush Yadav, Vinay kumar Deepak, Divyansh Singh. Analysis of Bioinformatics Software Applied in Computer-Aided Drug Design. Research & Reviews: A Journal of Drug Design & Discovery. 2024; ():-.
How to cite this URL: Satish kumar Yadav, Mohd. Wasiullah, Piyush Yadav, Vinay kumar Deepak, Divyansh Singh. Analysis of Bioinformatics Software Applied in Computer-Aided Drug Design. Research & Reviews: A Journal of Drug Design & Discovery. 2024; ():-. Available from: https://journals.stmjournals.com/rrjoddd/article=2024/view=151743


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Received May 10, 2024
Accepted June 14, 2024
Published June 21, 2024
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