Mahendra Singh Rathore,
Bhaktraj Singh Chauhan,
Udita Singh,
Nidhi Kaushal Karva,
Deepali Pathak,
- Principal, Department of Clinical Pharmacy, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
- Assistant Professor, Department of Pharmacy Practice, Bhupal Nobles College of Pharmacy, Udaipur, Rajasthan, India
- Clinical Process Associate, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
- Assistant Professor, Geetanjali Medical College and Hospital, Udaipur, Rajasthan, India
- Drug Control Officer, Food Safety and Drug Control Organization, Udaipur, Rajasthan, India
Abstract
Context: Depression leads to more dysfunction and stress, which could affect the patient’s life condition. Tuberculosis is a leading cause of comorbidity with depression. Those suffering from tuberculosis and depression are at higher risk of bad health-seeking nature, resulting in higher morbidities, drug resistance, and mortality. The relationship is not well established.
Aims: To identify multiple variables/ dependent factors affecting depression respectively in tuberculosis patients and check the medication adherence among pulmonary tuberculosis patients using Morisky Scale. Settings and Design: A cross-sectional study was conducted at tertiary care hospital in Udaipur, Rajasthan. Methods and Material: A cross-sectional study was conducted in a tertiary care hospital at Udaipur, Rajasthan, between October 2021- July 2022. The cross-sectional study was performed on people with active pulmonary tuberculosis of 18 years and above who are on anti-tuberculotic medications. Results: The subjects with a mean age of 80.07±17.33 had moderately severe depression, and 52.07±17.3 had severe depression as per the PHQ-9 score. Out of 53 males, 12 were severely depressed, and out of 39 females, 13 had depression. The influence of medication adherence on tuberculosis patients with depression showed a negative correlation i,e; (R= -762). The correlation findings were found to be significant (0.01). Our results were consistent with the expected hypothesis, and finally, a substantial interaction between tuberculosis patients and depression was observed. Conclusions: We noticed a significant association between pulmonary tuberculosis and depression. Also, the study interpreted that low medication adherence to anti-tuberculosis treatment may lead to severe depression.
Keywords: Tuberculosis, Depression, Medication Adherence, pulmonary tuberculosis, Major depressive disorder, Morisky Medication Adherence Scale, PHQ-9 Scale.
[This article belongs to International Journal of Pathogens(ijpg)]
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Volume | 01 |
Issue | 02 |
Received | June 19, 2024 |
Accepted | July 5, 2024 |
Published | July 31, 2024 |