BIOACTIVE COMPOUNDS IN ETHANOLIC EXTRACT OF Strychnos innocua ROOT USING GAS CHROMATOGRAPHY AND MASS SPECTROMETRY (GC-MS)

Year : 2023 | Volume :01 | Issue : 01 | Page : 9-14
By

Alagbe John Olujimi

  1. Researcher Department of Animal Nutrition and Biochemistry,, Sumitra Research Institute Gujarat India

Abstract

Medicinal plants are of great relevance with endless pharmaceutical and therapeutic properties. They are source of wide array of secondary metabolites or bioactive compounds/phytochemicals (phenols, alkaloids, flavonoids, terpenoids, tannins, steroids and saponins) which are capable of discharging numerous biological functions (antimicrobial, antioxidant, antiviral, antifungal, anti-fibrotic, immune-modulatory, cytotoxic, antipyretic, antitumor, antihelminthic, antiprotozoal, antibacterial and so on). The use of gas chromatography and mass spectrometry analysis in identifying the bioactive compounds in ethanolic extract of Strychnos innocua root is a fundamental technique in quantifying the unknown samples, trace elements and contaminants leading to the discovery of novel compounds of pharmaceutical and biomedical importance. Result obtained showed that Strychnos innocua root extract contains 39 bioactive compounds with α-Cubebene (20.09 %) having the highest concentration followed by Dibutyl benzene -1,2 – dicarboxylate (10.17 %), β-Elemenone (10.02 %), 4-Methoxy-2-nitroformanilide (7.21 %), 1-Methyl cyclopropane methanol (5.96 %), 1, 3 propanediol, 2-ethyl 2-hydroxymethyl (3.71 %), Azelaic acid (2.87 %), Glycidol stearate (2.85 %), Chloromethyl 2-chlorodecanoate (2.83 %) and γ-terpinene (2.56 %) respectively. The remaining 29 bioactive compounds have concentrations less than 2 %. It was concluded that all the compounds observed are sources of medication that can be used traditionally in the treatment of human and animal diseases.

Keywords: Strychnos innocua, Phytochemicals, Pharmaceuticals, Therapeutics, Gas chromatography

[This article belongs to International Journal of Biochemistry and Biomolecule Research(ijbbr)]

How to cite this article: Alagbe John Olujimi. BIOACTIVE COMPOUNDS IN ETHANOLIC EXTRACT OF Strychnos innocua ROOT USING GAS CHROMATOGRAPHY AND MASS SPECTROMETRY (GC-MS). International Journal of Biochemistry and Biomolecule Research. 2023; 01(01):9-14.
How to cite this URL: Alagbe John Olujimi. BIOACTIVE COMPOUNDS IN ETHANOLIC EXTRACT OF Strychnos innocua ROOT USING GAS CHROMATOGRAPHY AND MASS SPECTROMETRY (GC-MS). International Journal of Biochemistry and Biomolecule Research. 2023; 01(01):9-14. Available from: https://journals.stmjournals.com/ijbbr/article=2023/view=128229

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Regular Issue Subscription Original Research
Volume 01
Issue 01
Received January 8, 2023
Accepted January 17, 2023
Published December 2, 2023
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