Sustainable Green Solvents: Ionic Liquid-Based Hydrogels

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Year : 2026 | Volume : 14 | 02 | Page :
    By

    Nidhi Jain,

  • Sonali Bhosle,

  • Smita Suhane,

  • Seema Tiwari,

  • Nidhi Yadav,

  1. Assistant Professor, Department of Engineering Science, Bharati Vidyapeeth College of Engineering, Lavale, Pune, Maharashtra, India
  2. Assistant Professor, Department of Electronics and Telecommunication, Army Institute of Technology, Dighi Hills, Pune, Maharashtra, India
  3. Associate Professor, Department of Engineering, Dr. D. Y. Patil Institute of Technology, Sant Tukaram Nagar, Pimpri, Pune, Maharashtra, India
  4. Associate Professor, Department of Electronics and Telecommunication, Army Institute of Technology, Dighi Hills, Pune, Maharashtra, India
  5. Assistant Professor, Department of Electronics and Telecommunication, Army Institute of Technology, Dighi Hills, Pune, Maharashtra, India

Abstract

Green solvents have been widely used in a wide range of applications, such as catalysis, separation sciences, energy storage and pharmaceutical applications. The main ingredient in the collection of the environmentally benign reagents is ionic liquids (ILs). Ionic liquid-based hydrogels are being used in the biological sciences and medicinal chemistry fields because of their excellent biocompatibility and biosafety features. The versatility of ionic liquids is great, as they can be formulated as membranes, surfactants, polymers or monomers. Due to the increased demand for sanitary, practical, and sustainable energy technology, energy emission monitoring is currently considered an object of study for the study of gels synthesized through ionic liquids. This fixation is particularly pronounced in the development of systems for energy storage which are subject to fluctuating operational conditions. The present review deals extensively with these areas, analyzing many of the procedures using ionic liquid ingredients. Illustrates the various application of Ionic liquid-based hydrogel for Storage and conversion of energy at Solar Cell Applications, Electrochromic Devices, Environmental and Catalysis Applications. Biomedical Applications of Ionic Liquid-Based Hydrogels such as Antimicrobial Properties, Drug Delivery Hemostasis, and Adhesion Wound Healing and also discussed briefly in the research paper. It also throws light on sustainable green solvents-Ionics liquids-based Hydrogels and its application in various fields.

Keywords: Hydrogels; Ionic liquids; Green solvents; Biomedical applications; Energy storage; Catalysis

How to cite this article:
Nidhi Jain, Sonali Bhosle, Smita Suhane, Seema Tiwari, Nidhi Yadav. Sustainable Green Solvents: Ionic Liquid-Based Hydrogels. Journal of Polymer & Composites. 2026; 14(02):-.
How to cite this URL:
Nidhi Jain, Sonali Bhosle, Smita Suhane, Seema Tiwari, Nidhi Yadav. Sustainable Green Solvents: Ionic Liquid-Based Hydrogels. Journal of Polymer & Composites. 2026; 14(02):-. Available from: https://journals.stmjournals.com/jopc/article=2026/view=240955


References

  1. El‑Hefian EA, Nasef MM, Yahaya AH. Preparation and characterization of chitosan/polyvinyl alcohol blends—a rheological study. E‑J Chem. 2010;7:S349. doi:10.1155/2010/275135.
  2. Khan A, Othman MBH, Razak KA, Akil HM. Synthesis and physicochemical investigation of chitosan‑PMAA‑based dual‑responsive hydrogels. J Polym Res. 2013;20:273. doi:10.1007/s10965-013-0273-7.
  3. Rosiak JM, Yoshii F. Hydrogels and their medical applications. Nucl Instrum Methods Phys Res B. 1999;151:56–64. doi:10.1016/S0168-583X(99)00118-4.
  4. Welton T. Room‑temperature ionic liquids: solvents for synthesis and catalysis. Chem Rev. 1999;99:2071–2083. doi:10.1021/cr980032t.
  5. Moshikur RM, Chowdhury MR, Moniruzzaman M, Goto M. Biocompatible ionic liquids and their applications in pharmaceutics. Green Chem. 2020;22:8116–8139. doi:10.1039/D0GC02387F.
  6. Freemantle M. Designer solvents: ionic liquids may boost clean technology development. Chem Eng News. 1998;76:32–37.
  7. Rogers RD, Seddon KR. Ionic liquids—solvents of the future. 2003;302:792–793. doi:10.1126/science.1090313.
  8. Bae J, Park J, Kim S, Cho H, Kim HJ, Park S, et al. Tailored hydrogels for biosensor applications. J Ind Eng Chem. 2020;89:1–12. doi:10.1016/j.jiec.2020.05.001.
  9. Ghorbanizamani F, Timur S. Ionic liquids from biocompatibility and electrochemical aspects toward applying in biosensing devices. Anal Chem. 2018;90:640–648. doi:10.1021/acs.analchem.7b03596.
  10. Zhang B, Sudre G, Quintard G, Serghei A, David L, Bernard J, et al. Guar gum as biosourced building block to generate highly conductive and elastic ionogels. Carbohydr Polym. 2017;157:586–595. doi:10.1016/j.carbpol.2016.10.050.
  11. Benight SJ, Wang C, Tok JBH, Bao Z. Stretchable and self‑healing polymers for electronic skin. Prog Polym Sci. 2013;38:1961–1977. doi:10.1016/j.progpolymsci.2013.08.001.
  12. Keplinger C, Sun JY, Foo CC, Rothemund P, Whitesides GM, Suo Z. Stretchable, transparent, ionic conductors. 2013;341:984–987. doi:10.1126/science.1240228.
  13. Tang B, White SP, Frisbie CD, Lodge TP. Synergistic increase in ionic conductivity of ion gels. 2015;48:4942–4950. doi:10.1021/acs.macromol.5b00882.
  14. Fullerton‑Shirey SK, Maranas JK. Effect of LiClO₄ on PEO‑based solid polymer electrolytes. 2009;42:2142–2156. doi:10.1021/ma802502u.
  15. Gu Y, Zhang S, Martinetti L, Lee KH, McIntosh LD, Frisbie CD, et al. High‑toughness ion gels by triblock copolymer self‑assembly. J Am Chem Soc. 2013;135:9652–9655. doi:10.1021/ja4051394.
  16. Zhou C, Sheng C, Gao L, Guo J, Li P, Liu B. Poly(ionic liquid) hydrogels for wound healing. Chem Eng J. 2021;413:127429. doi:10.1016/j.cej.2020.127429.
  17. Sun J, Yuan Y, Lu G, Li L, Zhu X, Nie J. Self‑adhesive ionogel‑based strain sensor. J Mater Chem C. 2019;7:11244–11250. doi:10.1039/C9TC03797G.
  18. Fang Y, Cheng H, He H, Wang S, Li J, Yue S, et al. Stretchable ionogels with high thermoelectric properties. Adv Funct Mater. 2020;30:2004699. doi:10.1002/adfm.202004699.
  19. Duflo S, Thibeault SL, Li W, Shu XZ, Prestwich GD. Vocal fold repair using synthetic ECM. Tissue Eng. 2006;12:2171–2180. doi:10.1089/ten.2006.12.2171.
  20. Chen K, Wu Z, Liu Y, Yuan Y, Liu C. Injectable adhesive hydrogels for joint wounds. Adv Funct Mater. 2022;32:2110066. doi:10.1002/adfm.202110066.
  21. Liang Y, Wang K, Li J, Wang H, Xie XQ, Cui Y, et al. Supramolecular eutectogels for sensors. Adv Funct Mater. 2021;31:2104963. doi:10.1002/adfm.202104963.
  22. Wei J, Zheng Y, Chen T. Hydrophobic ionogel for underwater sensors. Mater Horiz. 2021;8:2761–2770. doi:10.1039/D1MH01103K.
  23. Boateng J, Catanzano O. Advanced wound dressings. J Pharm Sci. 2015;104:3653–3680. doi:10.1002/jps.24610.
  24. Guo S, DiPietro LA. Factors affecting wound healing. J Dent Res. 2010;89:219–229. doi:10.1177/0022034509359125.
  25. Velnar T, Bailey T, Smrkolj V. Wound healing mechanisms. J Int Med Res. 2009;37:1528–1542. doi:10.1177/147323000903700531.
  26. Han S, Wu Q, Xu Y, Zhang J, Chen A, Chen Y, et al. Ionogels for wearable electronics. Adv Mater Technol. 2023;8:2301123. doi:10.1002/admt.202301123.
  27. Lei K, Chen M, Guo P, Fang J, Zhang J, Liu X, et al. Stretchable ionogels. Adv Funct Mater. 2023;33:2303511. doi:10.1002/adfm.202303511.
  28. Yang JY, Tsai YL, Cheng TH, Su YL, Hong YK, Kuo LC, et al. Ionic liquid‑based hydrogels for biomedical use. Chem Eng J. 2025;515:163849. doi:10.1016/j.cej.2024.163849.
  29. Liang J, Li J, Zhou C, Jia W, Song H, Zhang L, et al. Imidazolium‑based antimicrobial hydrogels. Acta Biomater. 2019;99:133–140. doi:10.1016/j.actbio.2019.09.003.
  30. Liu P, Jin K, Wong W, Wang Y, Liang T, He M, et al. Antibacterial hydrogel dressing with electrical stimulation. Chem Eng J. 2021;415:129025. doi:10.1016/j.cej.2021.129025.
  31. Rizzo C, Arrigo R, Dintcheva NT, Gallo G, Giannici F, Noto R, et al. Supramolecular hydro‑ and ionogels. Chem Eur J. 2017;23:16297–16311. doi:10.1002/chem.201703288.
  32. Zheng Z, Guo J, Mao H, Xu Q, Qin J, Yan F. Metal‑containing poly(ionic liquid) membranes. ACS Biomater Sci Eng. 2017;3:922–928. doi:10.1021/acsbiomaterials.7b00109.
  33. Xu Q, Zheng Z, Wang B, Mao H, Yan F. Zinc‑coordinated poly(ionic liquid) membranes. ACS Appl Mater Interfaces. 2017;9:14656–14664. doi:10.1021/acsami.7b02007.
  34. Zhou C, Sheng C, Gao L, Guo J, Li P, Liu B. Poly(ionic liquid) hydrogels for wound healing. Chem Eng J. 2021;413:127429. doi:10.1016/j.cej.2020.127429.
  35. He X, Dong J, Zhang X, Bai X, Zhang C, Wei D. Choline‑based self‑healing ionic hydrogels. Chem Eng J. 2022;435:135168. doi:10.1016/j.cej.2022.135168.
  36. Vaidya A, Mitragotri S. Ionic liquid‑mediated insulin delivery. J Control Release. 2020;327:26–34. doi:10.1016/j.jconrel.2020.07.037.
  37. Kuddushi M, Patel NK, Rajput S, El Seoud OA, Mata JP, Malek NI. Temperature‑responsive ionic liquid gelator. 2020;2:e1900048. doi:10.1002/syst.201900048.
  38. Liu H, Shi X, Wu D, Khshen FK, Deng L, Dong A, et al. Injectable thermosensitive hydrogel for tumor prevention. ACS Appl Mater Interfaces. 2019;11:19700–19711. doi:10.1021/acsami.9b04663.
  39. Zheng Y, Cheng Y, Chen J, Ding J, Li M, Li C, et al. Injectable hydrogel‑microsphere chemotherapy. ACS Appl Mater Interfaces. 2017;9:3487–3496. doi:10.1021/acsami.6b13759.
  40. Bankmann D, Giernoth R. Magnetic resonance spectroscopy in ionic liquids. Prog Nucl Magn Reson Spectrosc. 2007;51:63–90. doi:10.1016/j.pnmrs.2007.02.007.
  41. Wilkes JS. Short history of ionic liquids. Green Chem. 2002;4:73–80. doi:10.1039/B110838G.
  42. Ullah F, Othman MBH, Javed F, Ahmad Z, Akil HM. Classification and applications of hydrogels. Mater Sci Eng C. 2015;57:414–433. doi:10.1016/j.msec.2015.07.053.
  43. Kuddushi M, Patel NK, Rajput S, El Seoud OA, Mata JP, Malek NI. Temperature‑responsive low molecular weight ionic liquid‑based gelator: an approach to fabricate an anticancer drug‑loaded hybrid ionogel. 2020;2:e1900048. doi:10.1002/syst.201900048.
  44. Liu H, Shi X, Wu D, Khshen FK, Deng L, Dong A, et al. Injectable, thermosensitive nanoparticle‑aggregated hydrogel with tumor‑specific targeting, penetration, and release for efficient postsurgical prevention of tumor recurrence. ACS Appl Mater Interfaces. 2019;11:19700–19711. doi:10.1021/acsami.9b04663.
  45. Zheng Y, Cheng Y, Chen J, Ding J, Li M, Li C, et al. Injectable hydrogel–microsphere construct with sequential degradation for locally synergistic chemotherapy. ACS Appl Mater Interfaces. 2017;9:3487–3496. doi:10.1021/acsami.6b13759.
  46. Egorova KS, Gordeev EG, Ananikov VP. Biological activity of ionic liquids and their application in pharmaceutics and medicine. Chem Rev. 2017;117:7132–7189. doi:10.1021/acs.chemrev.6b00562.
  47. Bankmann D, Giernoth R. Magnetic resonance spectroscopy in ionic liquids. Prog Nucl Magn Reson Spectrosc. 2007;51:63–90. doi:10.1016/j.pnmrs.2007.02.007.
  48. Wilkes JS. A short history of ionic liquids—from molten salts to neoteric solvents. Green Chem. 2002;4:73–80. doi:10.1039/B110838G.
  49. Chen N, Zhang H, Li L, Chen R, Guo S. Ionogel electrolytes for high‑performance lithium batteries: a review. Adv Energy Mater. 2018;8:1702675. doi:10.1002/aenm.201702675.
  50. Mekonnen Y, Sundararajan A, Sarwat AI. A review of cathode and anode materials for lithium‑ion batteries. 2016;1–6.
  51. Osada I, de Vries H, Scrosati B, Passerini S. Ionic‑liquid‑based polymer electrolytes for battery applications. Angew Chem Int Ed. 2015;55:500–513. doi:10.1002/anie.201511384.
  52. Ashby DS, DeBlock R, Lai CH, Choi CS, Dunn BS. Patternable, solution‑processed ionogels for thin‑film lithium‑ion electrolytes. 2017;1:344–358. doi:10.1016/j.joule.2017.08.012.
  53. Ma Y, Li L, Gao G, Yang X, You J, Yang P. Ionic conductivity enhancement in gel polymer electrolyte membranes using ionic liquid for lithium‑ion batteries. Colloids Surf A Physicochem Eng Asp. 2016;502:130–138. doi:10.1016/j.colsurfa.2016.05.007.
  54. Abbas Q, Mirzaeian M, Hunt MR. Materials for sodium‑ion batteries. Ref Modul Mater Sci Mater Eng. 2020;17:106–114. doi:10.1016/B978‑0‑12‑803581‑8.11718‑1.
  55. Mei J, Liao T, Ayoko GA, Bell J, Sun Z. Cobalt oxide‑based nanoarchitectures for electrochemical energy applications. Prog Mater Sci. 2019;103:596–677. doi:10.1016/j.pmatsci.2019.03.001.
  56. Moreno M, Simonetti E, Appetecchi GB, Carewska M, Montanino M, Kim GT, et al. Ionic liquid electrolytes for safer lithium batteries. J Electrochem Soc. 2017;164:A6026–A6031. doi:10.1149/2.0051701jes.
  57. Schoetz T, Leung O, De Leon CP, Zaleski C, Efimov I. Aluminium deposition in EMImCl–AlCl₃ ionic liquid and ionogel for improved aluminium batteries. J Electrochem Soc. 2020;167:040516. doi:10.1149/1945‑7111/ab6bac.
  58. Stievano L, de Meatza I, Bitenc J, Cavallo C, Brutti S, Navarra MA. Emerging calcium batteries. J Power Sources. 2020;482:228875. doi:10.1016/j.jpowsour.2020.228875.
  59. Arroyo‑de Dompablo ME, Ponrouch A, Johansson P, Palacín M. Achievements, challenges, and prospects of calcium batteries. Chem Rev. 2020;120:6331–6357. doi:10.1021/acs.chemrev.9b00339.
  60. Ji B, He H, Yao W, Tang Y. Recent advances and perspectives on calcium‑ion storage: key materials and devices. Adv Mater. 2021;33:e2005501. doi:10.1002/adma.202005501.
  61. Eh AL‑S, Tan AWM, Cheng X, Magdassi S, Lee PS. Recent advances in flexible electrochromic devices: prerequisites, challenges, and prospects. Energy Technol. 2018;6:33–45. doi:10.1002/ente.201700705.
  62. More PP, Rathod PV, Puguan JMC, Kim H. All‑in‑one display device with multicolor states derived from hybrid ionogel material. Dyes Pigments. 2021;195:109730. doi:10.1016/j.dyepig.2021.109730.
  63. Sun J, Jin Z, Wang J, Wang H, Zhang Q, Gao H, et al. Ionic liquid cross‑linked hydrogel for removing heavy metal ions from water. Polymers (Basel). 2023;15:2784. doi:10.3390/polym15132784.
  64. Lv Q, Hu X, Shen Y, Sun G. Polymer hydrogel cross‑linked by inorganic nanoparticles for removing trace metal ions. J Appl Polym Sci. 2020;137:49004. doi:10.1002/app.49004.
  65. Asbani B, Bounor B, Robert K, Douard C, Athouël L, Lethien C, et al. Reflow soldering‑resistant solid‑state 3D micro‑supercapacitors based on ionogel electrolyte. J Electrochem Soc. 2020;167:100551. doi:10.1149/1945‑7111/abb382.
  66. Karuppasamy K, Theerthagiri J, Vikraman D, Yim CJ, Hussain S, Sharma R, et al. Ionic liquid‑based electrolytes for energy storage devices: a brief review. Polymers (Basel). 2020;12:918. doi:10.3390/polym12040918.
  67. Chang WQ, Apodaca DC, Peng WC, Yang YC. Protic ionic liquid‑containing silica‑based ionogels for non‑humidified PEMFC applications. 2018;24:469–481. doi:10.1007/s11581‑017‑2279‑5.
  68. Zou M, Luo J, Wang X, Tan S, Wang C, Wu Y. In situ polymerized protic ionogels for fuel cells at elevated temperatures. Ind Eng Chem Res. 2021;60:3589–3596. doi:10.1021/acs.iecr.0c05840.
  69. Liu X, Sun Y, Tong Y, Wang X, Zheng J, Wu Y, et al. Materials and electrolytes for metal‑ion‑based hybrid capacitors: a review. Nano Energy. 2021;86:106070. doi:10.1016/j.nanoen.2021.106070.
  70. Ruan J, Mo F, Chen Z, Liu M, Zheng S, Wu R, et al. Nitrogen‑doped hierarchical dual‑carbon for potassium‑ion hybrid capacitors. Adv Energy Mater. 2020;10:1904045. doi:10.1002/aenm.201904045.
  71. Benedetti TM, Carvalho T, Iwakura DC, Braga F, Vieira BR, Vidinha P, et al. All solid‑state electrochromic device using gelatin‑based ionogel. Sol Energy Mater Sol Cells. 2015;132:101–106. doi:10.1016/j.solmat.2014.09.029.
  72. Khanmirzaei MH, Ramesh S, Ramesh K. Hydroxypropyl cellulose‑based gel polymer electrolytes for dye‑sensitized solar cells. Sci Rep. 2015;5:18056. doi:10.1038/srep18056.
  73. Kholany M, et al. Bio-based solvents as a sustainable alternative to develop a multiproduct biorefinery process from archaebacteria Halobacterium salinarum Green Chem. 2024;26(5):2793–2806.
  74. Shi Y, Wang M, Ma C, Wang Y, Li X, Yu G. A conductive self-healing hybrid gel enabled by metal–ligand supramolecule and nanostructured conductive polymer. Nano Lett. 2015;15:6276–6281.
  75. Chu L, Liu C, Zhou G, Xu R, Tang Y, Zeng Z, Luo S. A double network gel as low cost and easy recycle adsorbent: Highly efficient removal of Cd(II) and Pb(II) pollutants from wastewater. J Hazard Mater. 2015;300:153–160.
  76. Li J, Illeperuma WRK, Suo Z, Vlassak JJ. Hybrid hydrogels with extremely high stiffness and toughness. ACS Macro Lett. 2014;3:520–523.
  77. Shi Y, Wang M, Ma C, Wang Y, Li X, Yu G. A conductive self-healing hybrid gel enabled by metal–ligand supramolecule and nanostructured conductive polymer. Nano Lett. 2015;15:6276–6281.
  78. Yadav D, Nain K, Dhillayan D, Mittal R, Santosh B, Bhukal S. Hydrophobic ionic liquid (IL)-based magnetic adsorbents: The way forward to remediate water pollution. Environ Sci Adv. 2024;3:480–501.
Ahead of Print Subscription Review Article
Volume 14
02
Received 03/04/2026
Accepted 20/04/2026
Published 25/04/2026
Publication Time 22 Days
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