Preparation of Organic Compounds by Microwave Technique with Applications

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Year : 2025 | Volume : 16 | 02 | Page : –
    By

    Dr. Nagham Mahmood Aljamali,

  • Dr. Ali Jassim Al-Zuhairi,

  • Dr. Shireen Ridha Rasool,

  • Dr. Rajaa Abdul Ameerghafil,

  1. Assistant Professor, Ph.D., Organic Chemistry, Synthetic Chemistry Field, , Iraq
  2. Assistant Professor, College of Engineering, Al-Musayab, University of Babylon, Babylon, Iraq
  3. Assistant Professor, Department of Chemistry, College of Science ,University of Babylon, Babylon, Iraq
  4. Assistant Professor, Department of chemistry , College Education for Girls, Mosul, Iraq

Abstract

Microwaves are an influential, reliable energy basis that may be adapted to several functions. Recognizing the fundamental technique following for microwaves will supply the chemical researchers  with the right equipment and knowledge to be skilled to effectively apply microwave energy to any synthetic path. For chemical reactions and processes, microwaves offer an alternate energy source. Reaction mixtures are heated uniformly without coming into touch with walls using dielectric heating. While preserving respectable percentage yields and selectivity, the reaction time is greatly shortened in comparison to systems that are typically heated (heat). One small disadvantage is that, compared to heat heating, chemical reactions and processes in the microwave spectrum are more reliant on the tools and materials utilized. Percy Spencer was engaged in a radar-related project in the 1940s. He discovered that the chocolate bar in his pocket melted more quickly than he had anticipated while testing a new vacuum tube. He started pointing the tube at other items, such popcorn and eggs, out of curiosity to see what would happen. After these objects became hot, Spencer realized that microwave energy could have an interesting new application. The microwave oven was soon invented.

Keywords: Microwave, no solvent, purity, organic compound, less pollution.

How to cite this article:
Dr. Nagham Mahmood Aljamali, Dr. Ali Jassim Al-Zuhairi, Dr. Shireen Ridha Rasool, Dr. Rajaa Abdul Ameerghafil. Preparation of Organic Compounds by Microwave Technique with Applications. Journal of Modern Chemistry & Chemical Technology. 2025; 16(02):-.
How to cite this URL:
Dr. Nagham Mahmood Aljamali, Dr. Ali Jassim Al-Zuhairi, Dr. Shireen Ridha Rasool, Dr. Rajaa Abdul Ameerghafil. Preparation of Organic Compounds by Microwave Technique with Applications. Journal of Modern Chemistry & Chemical Technology. 2025; 16(02):-. Available from: https://journals.stmjournals.com/jomcct/article=2025/view=201518



References

  1. Neas, E.D.; Collins, M.J. Introduction to Microwave Sample Preparation Theory and Practice, Kingston, H.M.; Jassie, L.B., Eds., American Chemical Society 1988, ch. 2, pp. 7-32.
  2. Gedye, R.; Smith, F.; Westaway, K.; Ali, H.; Baldisera, L.; Laberge, L.; Rousell, J. The use of microwave ovens for rapid organic synthesis. Tetrahedron Lett. 1986, 27, pp. 279-82.
  3. Pan, H.; Yao, C.; Yao, S.; Yang, W.; Wu, W.; Guo, D. A Metabolomics Strategy for Authentication of Plant Medicines with Multiple Botanical Origins, a Case Study of Uncariae Rammulus Cum Uncis. J. Sep. Sci. 2020, 43, 1043– 1050,  DOI: 10.1002/jssc.201901064
  4. N Mahmood A . Effect of Conditions and Catalysis on Products ., 2021; 1st Ed, Eliva Press SRL., ISBN: 9781636482286
  5. Giguere, R.J.; Bray, T.L.; Duncan, S.M.; Majetich, G. Application of commercial microwave ovens to organic synthesis. Tetrahedron Lett. 1986, 27, pp. 4945-48.
  6. N Mahmood A . Alternative Methods in Organic Synthesis. Eliva Press SRL. 2020; 1st Ed. ISBN: 9798680201176.
  7. Loupy, A.; Perreus, L.; Liagre, M.; Burle, K.; Moneuse, M. “Reactivity and selectivity under microwaves in organic chemistry. Relation with medium effects and reaction mechanisms.” Pure Appl. Chem. 2001, 73, pp. 161-66
  8. Nagham M A. The Various Preparation Methods in Synthetic Chemistry. Evincepub Publishing house. 2019; 1st Ed. ISBN: 978-93-88277-82-2.
  9. Alsbr IKA, Abdullabass HK, N Mahmood A. Invention of (Gluta.Sulfazane-Cefixime) Compounds as Inhibitors of Cancerous Tumors. Journal of Cardiovascular Disease Research. 2020; 11(2): 44-55.
  10. Nagham M A. Synthesis of Antifungal Chemical Compounds from Fluconazole with (Pharma-Chemical) Studying. Research journal of Pharmaceutical, biological and chemical sciences. 2017; 8(3): 564-573.
  11. Hall, L. M.; Hill, D. W.; Bugden, K.; Cawley, S.; Hall, L. H.; Chen, M.-H.; Grant, D. F. Development of a Reverse Phase Hplc Retention Index Model for Nontargeted Metabolomics Using Synthetic Compounds. J. Chem. Inf. Model. 2018, 58, 591– 604,  DOI: 10.1021/acs.jcim.7b00496
  12. Tada R, Chavda N, Shah MK. Synthesis and characterization of some new thiosemicarbazide derivatives and their transition metal complexes. J Chem Pharm Res. 2011; 3: 290–297.
  13. N Mahmood A. 2016. Synthesis and Biological Study of Hetero (Atoms and Cycles) Compounds., Der Pharma Chemica, 8,6, 40-48.
  14. Hasaneen K Abdullabass, Aseel M Jawad ,N Mahmood A. Synthesis of drugs derivatives as inhibitors of cancerous cells., Biochem. Cell. Arch, Vol. 20 (2) – October 2020., DocID: https://connectjournals.com/03896.2020.20.5315
  15. N Mahmood Aljamali, Intisar O Alfatlawi. Synthesis of Sulfur Heterocyclic Compounds and Study of Expected Biological Activity .,  Research J. Pharm. and Tech., 2015, 8,9 ,1225-1242 , DOI: 10.5958/0974-360X.2015 .00224.3.
  16. N Mahmood A , Alsbr IA. Development of Trimethoprim Drug and Innovation of Sulfazane-Trimethoprim Derivatives as Anticancer Agents. Biomedical & Pharmacology Journal. 2020; 13(2): 613-625.
  17. Alfatlawi I O, N Mahmood A ,Nuha SS, Zainab MJ. Synthesis of New Organic Compounds Via Three Components Reaction with Studying of (Identification, Thermal Behavior, Bioactivity on Bacteria of Teeth). Journal of Global Pharma Technology. 2017; 11(9): 157-164.
  18. N Mahmood A.; S M Jawd.; Zainab M J.; Intisar O Alfatlawi.  2017 . Inhibition activity of (Azo–acetyl acetone) on bacteria of mouth., Research Journal of Pharmacy and Technology 10(6):1683-1686, DOI: 10.5958/0974-360X.2017.00297.9 .
  19. Jawad, N M Aljamali . Preparation, Investigation and Study of Biological Applications of Tyrosine Derivatives against Breast Cancer Cells ., NeuroQuantology ,September 2021 ,Volume 19 , Issue 9 , Page 117-125 .,doi: 10.14704/nq.2021.19.9.NQ21144
  20. Jawad AM, Nagham M A, Jawd SM. Development and Preparation of ciprofloxacin Drug Derivatives for Treatment of Microbial Contamination in Hospitals and Environment. Indian Journal of Forensic Medicine & Toxicology. 2020: 14(2): 1115-1122.
  21. Kalapala V, Banothu V, Chandra SKB, et al. Synthesis and characterization of some new thiosemicarbazide derivatives and their transition metal complexes. J Chem Pharm Res. 2015; 7: 437–445.
  22. Nagham Mahmood A. 2015. Synthesis and Chemical Identification of Macro Compounds of (Thiazol and Imidazol) .,Research J. Pharm. and Tech, 8,1, 78-84., DOI: 10.5958/0974-360X.2015.00016.5.
  23. Dakshayani K, Lingappa Y, Sayaji Rao M, et al. Synthesis, Characterization and Biological Activity of 5-Methyl, Thiophene-2-Carboxaldehyde Derivatives of Copper (II), Cobalt (II) and Nickel (II) Complexes. Res Pap Int J Chem Pharm Sci. 2012; 3: 50–55.
  24. N Mahmood A, Imd Karm . Development of Trimethoprim Drug and Innovation of Sulfazane-Trimethoprim Derivatives as Anticancer Agents ., Biomedical & Pharmacology Journal, March 2020.,Vol. 13,(2), p. 613-625., http://dx.doi.org/10.13005/bpj/1925
  25. Nagham M A. Survey on Methods of Preparation and Cyclization of Heterocycles. International Journal of Chemical and Molecular Engineering. 2020; 6(2): 19–36p.
  26. Faria, M.P. Ruiz, D.E. Resasco .Phase-selective catalysis in emulsions stabilized by Janus silica-nanoparticles., Adv. Synth. Catal., 352 (14-15) (2010), pp. 2359-2364.
  27. Naumann d’Alnoncourt, Raoul; Csepei, Lénárd-István; Hävecker, Michael; Girgsdies, Frank; Schuster, Manfred E.; Schlögl, Robert; Trunschke, Annette (2014). “The reaction network in propane oxidation over phase-pure MoVTeNb M1 oxide catalysts”. Journal of Catalysis. 311: 369–385 . doi:1016/j.jcat. 2013.12.008. hdl:11858/00-001M-0000-0014-F434-5 .
  28. N Mahmood A. Survey on Semicarbazide and Thiosemicarbazide Derivatives. International Journal of Chemical Synthesis and Chemical Reaction. 2021; 7(1): 51–57p., DOI: https://doi.org/10.37628/jcscr.v7i1.1083
  29. Rusul N., Jinan M H. (2023). Detection of Virulence Genes of Pathogenic Escherichia coli Isolated from Different Sources., Al-Harf Journal ., Issue August, No. 18, P: 130-138.
  30. Dhuha Raheem AA., Zainab Abd A M. (2023). Biosynthesis, characterization, Antioxidant and Antihemolysis activity of Silver nanoparticles (AgNPs) produced using Cynophyta Alga Extract (Spirulina platensis)., Al-Harf Journal., Issue. November, No. 19
  31. Nagham M A. Creation of Originated Macrocyclic Sulfazan-Formazan Compounds and Linear Sulfazan-Formazan for the first Time Globally with their Assay as Antifungal ., Biomedical Journal of Scientific & Technical Research., 2021, Volume 40-Issue 3, P: 32266-32272  ., DOI: 10.26717/BJSTR.2021.40.006453
  32. Mokrani, Touhami; van Reenen, Albert; Amer, Ismael (2015). “Molecular weight and tacticity effect on morphological and mechanical properties of Ziegler–Natta catalyzed isotactic polypropylenes”. Polímeros . 25 (6): 556–563. doi:1590/0104-1428.2158.
  33. Shireen R. Rasool, N Mahmood A, Ali Jassim Al-Zuhairi. Guanine substituted heterocyclic derivatives as bioactive compounds., Biochem. Cell. Arch. Vol. 20, Supplement 2, pp. 3651-3655, 2020 ., DocID: https://connectjournals.com/03896.2020.20.3651.
  34. N M Aljamali. Inventing of Macrocyclic Formazan Compounds and Studying Them Against Breast Cancer for The first Time Globally . Annals of pharma research .,9 ,7, (2021). Pp 525-533., Available at:https://www.annalsofpharmaresearch.com/index.php?journal=apr&page=article&op=view&path%5B%5D=38
  35. Nagham M A ,Nemah Sahib Muhammed . Chemo – Spectral and Biological Studying of New Ligands ., Research Journal of Pharmaceutical, Biological and Chemical Sciences .,May–June, 2017 , RJPBCS ,8,(3) ,Page No. 674.
  36. N Mahmood A, Jad F. Preparation, Diagnosis and Evaluation of Cyclic-Tryptophan Derivatives as Anti Breast Cancer Agents. Biomed Pharmacol J ., 2021; 14(4)., Available from: https://bit.ly/3HuvlVG
  37. N M Aljamali . Designation of Macrocyclic Sulfazan and Triazan as Originated Compounds with Their Estimation in Nano-Activities by the Scanning Microscope ., International Journal of Convergence in Healthcare, January-June 2022, Vol. 02, No. 01., P: 25-34 , Available at : https://www.ijcih.com/index.php/ijcih/article/view/21
  38. Nagham Mahmood A. Origination of Macrocyclic Formazan with Macrocyclic Sulfazan and Triazan as Originated Compounds and Compared Their efficiency Against Breast Cancer. Open Access Journal of Biomedical Science, 2022, 4(1) OAJBS.ID.000383. DOI: 10.38125/OAJBS.000383
  39. Nagham M A. Synthesis Innovative Cyclic Formazan Compounds for the First Time and Evaluation of Their Biological Activity. International Journal of Polymer Science & Engineering . 2021; 7(2): 5–14p., DOI: https://doi.org/10.37628/ijpse.v7i2.830 .; Available at : http://materials.journalspub.info/index.php?journal=JPMSE&page=article&op=view&path%5B%5D=830
  40. Brédas JL, Persson K, Seshadri R. Computational design of functional materials. Chem Mater. 2017;29(6):2399-2401.
  41. Olivares-Amaya R, Amador-Bedolla C, Hachmann J, Atahan-Evrenk S, Sanchez-Carrera RS, Vogt L, et al. Accelerated computational discovery of high-performance materials for organic photovoltaics by means of cheminformatics. Energy Environ Sci. 2011;4(12):4849-4861.
  42. Abdellah IM, Koraiem AI, El-Shafei A. Structure-property relationship of novel monosubstituted Ru (II) complexes for high photocurrent and high efficiency DSSCs: Influence of donor versus acceptor ancillary ligand on DSSCs performance. Sol Energy. 2019;177:642-651.
  43. Nagham M A. Inventing of Macrocyclic Formazan Compounds with Their Evaluation in Nano- Behavior in the Scanning Microscope and Chromatography. Biomedical Journal of Scientific & Technical Research. 41, (3), 2022., P: 32783-32792.; BJSTR. MS.ID.006616.; DOI: 10.26717/BJSTR.2022.41.006616 .
  44. N Mahmood A, Zainab Mohamed Farhan. (2022). Anticancer Study of Innovative Macrocyclic Formazan Compounds from Trimethoprim Drug ., Egyptian Journal of Chemistry ,2022 ., DOI:  21608/EJCHEM.2022.132514.5852
  45. Zainab Mohamed Farhan, N Mahmood A. Comparison of the efficiency of innovative formazan compound with innovative sulfazan against breast tumors. International Journal of Medicine Research, Volume 7, Issue 1, 2022, Pages 18-25., Available at : https://www.medicinesjournal.com/archives/2022/vol7/issue1/7-1-18
  46. Lund, J. A.; Brown, P. N.; Shipley, P. R. Differentiation of Crataegus Spp. Guided by Nuclear Magnetic Resonance Spectrometry with Chemometric Analyses. Phytochemistry. 2017, 141, 11– 19 ,  DOI: 10.1016/j.phytochem.2017.05.003

Ahead of Print Subscription Review Article
Volume 16
02
Received 01/02/2025
Accepted 12/02/2025
Published 21/02/2025
Publication Time 20 Days


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