Antimicrobial Resistance in Veterinary Medicine

Year : 2024 | Volume : | : | Page : –
By

Kashif Aqueel Rizvi,

  1. Student, Department: Warner College of Dairy Technology, Sam Higginbottom University of Agriculture, Technology and Sciences, Allahabad, Uttar Pradesh, India

Abstract

Antimicrobial resistance (AMR) is a worldwide public health issue that impacts both human and animal populations. The use of antibiotics in veterinary medicine plays a significant role in the development and spread of AMR, contributing to resistant pathogens that impact both animals and humans. Antibiotics are widely utilized in animal husbandry, not only for treating diseases but also for preventing illness and enhancing growth in livestock. While this practice supports animal health and productivity, it has contributed to the rise of antibiotic-resistant bacteria that can spread to humans through direct contact, consumption of contaminated food, and environmental routes. The misuse and excessive use of antibiotics in veterinary medicine speed up the development of resistant bacterial strains, making it harder to treat infections in both animals and humans. This article examines the mechanisms behind resistance development, emphasizing how antibiotic use in animals contributes to antimicrobial resistance in zoonotic pathogens like Salmonella, Campylobacter, and Escherichia coli. It also highlights the One Health approach, which acknowledges the interdependence of human, animal, and environmental health in addressing AMR. Case studies of methicillin-resistant Staphylococcus aureus (MRSA) in animals and multidrug-resistant Salmonella in poultry highlight the public health risks associated with veterinary antibiotic use.  Strategies for mitigating AMR, including reducing antibiotic usage, adopting better animal husbandry practices, and exploring alternatives such as vaccines and probiotics, are discussed. The role of veterinary professionals in promoting responsible antibiotic use through stewardship programs and public education is emphasized. In conclusion, addressing AMR requires a collaborative approach that involves both veterinary and human health sectors, underscoring the need for continued research, monitoring, and policy development to combat the AMR crisis effectively.

Keywords: Veterinary Medicine, AMR, conjugation, Transformation, penicillin.

How to cite this article:
Kashif Aqueel Rizvi. Antimicrobial Resistance in Veterinary Medicine. Research & Reviews : Journal of Veterinary Science and Technology. 2024; ():-.
How to cite this URL:
Kashif Aqueel Rizvi. Antimicrobial Resistance in Veterinary Medicine. Research & Reviews : Journal of Veterinary Science and Technology. 2024; ():-. Available from: https://journals.stmjournals.com/rrjovst/article=2024/view=180613

References

  1. Palma E, Tilocca B, Roncada P. Antimicrobial resistance in veterinary medicine: An overview. International journal of molecular sciences. 2020 Mar 11;21(6):1914.
  2. Caneschi A, Bardhi A, Barbarossa A, Zaghini A. The use of antibiotics and antimicrobial resistance in veterinary medicine, a complex phenomenon: A narrative review. Antibiotics. 2023 Mar 1;12(3):487.
  3. Garcia-Migura L, Hendriksen RS, Fraile L, Aarestrup FM. Antimicrobial resistance of zoonotic and commensal bacteria in Europe: the missing link between consumption and resistance in veterinary medicine. Veterinary Microbiology. 2014 May 14;170(1-2):1-9.
  4. McKellar QA. Antimicrobial resistance: a veterinary perspective. BMJ. 1998 Sep 5;317(7159):610-1.
  5. Schwarz S, Chaslus-Dancla E. Use of antimicrobials in veterinary medicine and mechanisms of resistance. Veterinary research. 2001;32(3-4):201-25.
  6. Tenover FC. Mechanisms of antimicrobial resistance in bacteria. The American journal of medicine. 2006 Jun 1;119(6):S3-10.
  7. Holmes AH, Moore LS, Sundsfjord A, Steinbakk M, Regmi S, Karkey A, Guerin PJ, Piddock LJ. Understanding the mechanisms and drivers of antimicrobial resistance. The Lancet. 2016 Jan 9;387(10014):176-87.
  8. Sefton AM. Mechanisms of antimicrobial resistance: their clinical relevance in the new millennium. Drugs. 2002 Mar;62:557-66.
  9. Levy SB. Active efflux mechanisms for antimicrobial resistance. Antimicrobial agents and chemotherapy. 1992 Apr;36(4):695-703.
  10. Levy SB. Active efflux mechanisms for antimicrobial resistance. Antimicrobial agents and chemotherapy. 1992 Apr;36(4):695-703.
  11. Sowash MG, Uhlemann AC. Community-associated methicillin-resistant Staphylococcus aureus case studies. Methicillin-Resistant Staphylococcus aureus (MRSA) Protocols. 2014:25-69.
  12. Smith RD, Yago M, Millar M, Coast J. A macroeconomic approach to evaluating policies to contain antimicrobial resistance: a case study of methicillin-resistant Staphylococcus aureus (MRSA). Applied health economics and health policy. 2006 Mar;5:55-65.
  13. Magalhães RJ, Loeffler A, Lindsay J, Rich M, Roberts L, Smith H, Lloyd DH, Pfeiffer DU. Risk factors for methicillin-resistant Staphylococcus aureus (MRSA) infection in dogs and cats: a case-control study. Veterinary research. 2010 Sep;41(5).
  14. Gieraltowski L, Higa J, Peralta VI, Green A, Schwensohn C, Rosen H, Libby T, Kissler B, Marsden-Haug N, Booth H, Kimura A. National outbreak of multidrug resistant Salmonella Heidelberg infections linked to a single poultry company. PloS one. 2016 Sep 15;11(9):e0162369.
  15. Karikari AB, Obiri-Danso K, Frimpong EH, Krogfelt KA. Multidrug resistant Campylobacter in faecal and carcasses of commercially produced poultry. African Journal of Microbiology Research. 2017 Feb 21;11(7):271-7.
  16. Varga C, Guerin MT, Brash ML, Slavic D, Boerlin P, Susta L. Antimicrobial resistance in Campylobacter jejuni and Campylobacter coli isolated from small poultry flocks in Ontario, Canada: A two-year surveillance study. PLoS One. 2019 Aug 29;14(8):e0221429.
  17. Santos-Ferreira N, Ferreira V, Teixeira P. Occurrence and multidrug resistance of Campylobacter in chicken meat from different production systems. Foods. 2022 Jun 21;11(13):1827.
  18. Advertis Agència. Why do antimicrobial resistances appear? The bacteria strategies for surviving antibiotics [Internet]. Small Ruminants. 2021 [cited 2024 Oct 28]. Available from: https://aboutsmallruminants.com/antimicrobial-resistances-strategies-antibiotics/

Ahead of Print Subscription Review Article
Volume
Received 18/10/2024
Accepted 26/10/2024
Published 30/10/2024