Dr. Minhaj Akhtar Usmani,
Dr. Kainat Akhtar Usmani,
- Associate Professor, Department of Food and Nutrition, Era University, Lucknow,, Uttar Pradesh, India
- Assistant Professor, Department of Commerce and Business Management, Integral University, Lucknow, Uttar Pradesh, India
Abstract
Cannabinoids, the bioactive compounds derived from the Cannabis sativa plant, have garnered increasing interest for their potential role as nutritional supplements. This abstract provides a succinct overview of Cannabinoids as Nutritional Supplements. This review delves into the multifaceted aspects of cannabinoids, particularly their interaction with the endocannabinoid system (ECS) and their potential health benefits. The exploration begins by elucidating the intricate relationship between cannabinoids and the ECS, a vital regulatory system in the human body responsible for maintaining homeostasis. The review examines the potential health benefits associated with cannabinoids as nutritional supplements, including anti-inflammatory properties, stress and anxiety reduction, appetite regulation, and potential neuroprotective effects. Safety considerations take center stage, addressing the importance of quality and purity in cannabinoid-based products. The paper emphasizes the necessity for rigorous testing and standardized dosing recommendations, considering individual variability and potential adverse effects. Furthermore, it underscores the evolving regulatory landscape, discussing the global legal status of cannabinoids and the challenges posed by varying regulations. Further research on them as a dietary supplement is needed to better understand the medical potential and safety of cannabis. Ongoing studies should focus on elucidating specific mechanisms of action within the ECS and exploring additional health benefits beyond those currently identified. As regulatory frameworks adapt globally, ensuring standardized production methods and clear labeling will be pivotal in promoting consumer trust and safety. Continued collaboration between researchers, regulators, and industry stakeholders is crucial for harnessing the benefits of cannabinoids while mitigating potential risks. Ultimately, this evolving field holds promise for novel therapeutic interventions, provided that scientific rigor and responsible oversight remain paramount. In conclusion, the paper highlights the dynamic nature of cannabinoids as a burgeoning field of research with promising implications for human health. As regulatory frameworks evolve, there is a need to strike a balance between guaranteeing consumer protection and providing access. The exploration of cannabinoids as nutritional supplements represents a multidimensional journey that necessitates continued research, responsible regulation, and informed consumer choices for the realization of their full potential.
Keywords: Cannabinoids, Cannabis sativa, anti-inflammatory properties, nutritional supplements
Dr. Minhaj Akhtar Usmani, Dr. Kainat Akhtar Usmani. Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape. Emerging Trends in Metabolites. 2024; ():-.
Dr. Minhaj Akhtar Usmani, Dr. Kainat Akhtar Usmani. Cannabinoids as Nutritional Supplements: Exploring The Potential Health Benefits and Regulatory Landscape. Emerging Trends in Metabolites. 2024; ():-. Available from: https://journals.stmjournals.com/etm/article=2024/view=175877
Fetching IP address…
References
- Walker LA, Koturbash I, Kingston R, ElSohly MA, Yates CR, Gurley BJ, Khan I. Cannabidiol (CBD) in dietary supplements: perspectives on science, safety, and potential regulatory approaches. Journal of Dietary Supplements. 2020 Sep 2;17(5):493-502.
- George F. Koob, Michael A. Arends, Michel Le Moal. In: George F. Koob, Michael A. Arends, Michel Le Moal, editor(s). Drugs, Addiction, and the Brain. Cambridge, Massachusetts, United States: Academic Press, 2014, Pages 261-308,
- Kaiser, S. and Monte, A. (2022), 13 – Management of cannabinoid hyperemesis syndrome—is it more than just avoiding cannabis use?, Editor(s): William L. Hasler, David J. Levinthal, Thangam Venkatesan, Cyclic Vomiting Syndrome and Cannabinoid Hyperemesis, Academic Press, Pg. 217-239, ISBN 9780128215975, https://doi.org/10.1016/B978-0-12-821597-5.00002-2. (https://www.sciencedirect.com/science/article/pii/B9780128215975000022).
- Harry, G. J., (2022), Chapter One – Cannabinoids, Editor(s): William Slikker, Michael Aschner, Lucio G. Costa, Advances in Neurotoxicology, Academic Press, Volume 8, Pages 1-48, ISSN 2468-7480, ISBN 9780323915854, https://doi.org/10.1016/bs.ant.2022.06.001. (https://www.sciencedirect.com/science/article/pii/S246874802200011X)
- Chilakapati, J.and Mehendale, H.M., Cannabinoids, Editor(s): Philip Wexler, Encyclopedia of Toxicology (Second Edition), Elsevier, 2005, Pages 405-407, ISBN 9780123694003, https://doi.org/10.1016/B0-12-369400-0/00175-7. (https://www.sciencedirect.com/science/article/pii/B0123694000001757).
- Bagshaw, S. M. and Hagen, N. A. Medical efficacy of cannabinoids and marijuana: a comprehensive review of the literature. J.Palliat.Care 2002;18(2):111-122.
- Carter GT, Ugalde V. Medical marijuana: emerging applications for the management of neurologic disorders. Physical Medicine and Rehabilitation Clinics. 2004 Nov 1;15(4):943-54.
- Leizer C, Ribnicky D, Poulev A, Dushenkov S, and Raskin I. The composition of hemp seed oil and its potential as an important source of nutrition. Journal of Nutraceuticals, Functional & Medical Foods 2000;2(4):35-53.
- Medicinal cannabis [Internet]. Healthdirect.gov.au. Healthdirect Australia; 2024. Available from: https://www.healthdirect.gov.au/medicinal-cannabis
- Therapeutic Effects and Indications for Cannabis Use | ATrain Education [Internet]. Atrainceu.com. 2016 . Available from: https://www.atrainceu.com/content/5-therapeutic-effects-and-indications-cannabis-use
- Cannabis (Marijuana) and Cannabinoids: What You Need To Know [Internet]. NCCIH. NCCIH; 2018. Available from: https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
- R. Preedy. Peroxisome Proliferator Activated Receptors and Cannabinoids. In V.R. Preedy editor, Handbook of Cannabis and Related Pathologies, United States: Academic Press, 2017, Pages 671-679
Volume | |
Received | June 1, 2024 |
Accepted | June 18, 2024 |
Published | June 27, 2024 |