Molecular Docking of Cocculus hirsutus Phytocompounds with the Selective DENV Virus Stereotypes

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    Prabhuram K, Shubham Wanarase

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    1. Student, Student,Department of Bioinformatics, Bionome, Department of Bioinformatics, Bionome,Karnataka, Karnataka,India, India

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    Abstract

    nDengue is a tropical disease with a high infection rate worldwide. Though treatments are available for the symptoms, anti-dengue drugs are unavailable. To tackle this issue, the study aims to shortlist the potential phytocompounds from Cocculus hirsutus medicinal plant, prevalent in South and South East Asia. Using molecular docking and ADME analysis, two potential compounds possessing high drug-likeness are identified namely, Sinococuline and Morphinan.

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    Keywords: DENV, NS1, anti-dengue, molecular docking

    n[if 424 equals=”Regular Issue”][This article belongs to International Journal of Genetic Modifications and Recombinations(ijgmr)]

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    [/if 424][if 424 equals=”Special Issue”][This article belongs to Special Issue under section in International Journal of Genetic Modifications and Recombinations(ijgmr)][/if 424][if 424 equals=”Conference”]This article belongs to Conference [/if 424]

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    Regular Issue Subscription Original Research

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    Volume 01
    Issue 01
    Received April 13, 2023
    Accepted May 6, 2023
    Published May 20, 2023

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